2022
DOI: 10.3389/fendo.2022.1036109
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Comparison of novel markers of metabolic complications and cardiovascular risk factors between obese non-diabetic and obese type 1 diabetic children and young adults

Abstract: IntroductionFor the past years, the prevalence of obesity is growing in the general population of children, as well as among diabetic patients, resulting in increased risk of cardiovascular complications. Type 1 diabetes mellitus (T1DM) is one of the most common chronic diseases in children and young adults, leading to decreased life quality and lifespan, with obesity being recognized recently as a major contributing factor to these health problems. The objective of this study was to analyze and compare the se… Show more

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Cited by 8 publications
(5 citation statements)
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“…Crianças obesas e portadoras de diabetes mellitus tipo 1 estão sujeitas a complicações, como o aumento de resistência insulínica em vários estágios da doença ao longo da vida, devido ao fato de possuírem excesso de peso. Essa complicação resulta em dificuldade no controle glicêmico, maiores quantitativos de hemoglobina glicada (HbA1c), maior perfil lipídico aterosclerótico e consequentemente surgimento precoce de microangiopatia e macroangiopatia (Kącka et al, 2022).…”
Section: Yang Et Al (2022)unclassified
“…Crianças obesas e portadoras de diabetes mellitus tipo 1 estão sujeitas a complicações, como o aumento de resistência insulínica em vários estágios da doença ao longo da vida, devido ao fato de possuírem excesso de peso. Essa complicação resulta em dificuldade no controle glicêmico, maiores quantitativos de hemoglobina glicada (HbA1c), maior perfil lipídico aterosclerótico e consequentemente surgimento precoce de microangiopatia e macroangiopatia (Kącka et al, 2022).…”
Section: Yang Et Al (2022)unclassified
“…Obesity is a high-risk factor for T1D and mostly encompasses the lifestyle factors which are also modifiable risk factors that lead to ED [91]. This study has investigated the influence of the BMI, body weight (BW), height (HT), and the mean age as risk factors of T1D-induced CVD in the Figure 8 (a-l) and in the Table 7.…”
Section: The Obesity Targets Are Also Fitting Biomarkers Of T1d-induc...mentioning
confidence: 99%
“…First, our study included only urban-based population and this might lead to different prevalence of obesity and growth status compared to rural population. Second, due to being a cross-sectional study, our percentiles for TMI cannot be implemented at future, because the prevalence of obesity is increasing among Iranian children (Kelishadi et al, 2014), and Z-score based on current studied population should be updated. Third, unfortunately we did not evaluate puberty hormonal status and Tanner stage, which can impact on the growth rates, height, and weight (Cole, 1986;Johnson et al, 2012).…”
Section: Study Limitationsmentioning
confidence: 99%
“…It is worth noting that the increasing rate of obesity has been greater among children compared to adult population (Collaborators et al, 2017). Obesity in childhood and adolescence contributes to several comorbidities which were previously considered as adult diseases, mainly cardiovascular and metabolic diseases (Daniels, 2009; Kącka et al, 2022; Lim et al, 2022; López‐Galisteo et al, 2022; Luca et al, 2022).…”
Section: Introductionmentioning
confidence: 99%
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