Comparison of outcomes in emergency department patients with suspected cardiac chest pain: two-centre prospective observational study in Southern China

Jiang, Hangjin; Li, Yunmei; Mo, Junrong; Chen, Xiaohui; Li, Min; Pan, Lin; Hung, Kevin Kei Ching; Rainer, Timothy; Graham, Colin A.

doi:10.1186/s12872-018-0814-4

“…However, none of the reviewed literature investigated the rate of AMI in the subgroup of repeated ED visitors. Many studies have focused on the number of ED visits due to chest pain as an outcome [25,34,[41][42][43][44][45][46][47][48][49][50] in the general ED population and have not focused on the subgroup of repeated patients. Furthermore, almost all of the reviewed studies had important exclusion criteria, e.g.…”

Section: Introductionmentioning

confidence: 99%

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2020

Journal of Clinical Cardiology

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an all-population based, one-month mortality rate of AMI between 8 to 24% [7,8] and an all-population based, one-year mortality rate of 19% [9]. Therefore, AMI has to be diagnosed or ruled out quickly. For this purpose, a fast clinical assessment including cardiac biomarker testing and the rapid execution of an electrocardiogram (ECG) are necessary. Based on the leading symptoms and clinical presentation, ECG-findings and in combination

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“…However, none of the reviewed literature investigated the rate of AMI in the subgroup of repeated ED visitors. Many studies have focused on the number of ED visits due to chest pain as an outcome [25,34,[41][42][43][44][45][46][47][48][49][50] in the general ED population and have not focused on the subgroup of repeated patients. Furthermore, almost all of the reviewed studies had important exclusion criteria, e.g.…”

Section: Introductionmentioning

confidence: 99%

Chest Pain in Repeated Emergency Department Visitors

Slankamenac¹,

Stucki²,

Keller³

2020

Journal of Clinical Cardiology

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an all-population based, one-month mortality rate of AMI between 8 to 24% [7,8] and an all-population based, one-year mortality rate of 19% [9]. Therefore, AMI has to be diagnosed or ruled out quickly. For this purpose, a fast clinical assessment including cardiac biomarker testing and the rapid execution of an electrocardiogram (ECG) are necessary. Based on the leading symptoms and clinical presentation, ECG-findings and in combination

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Impact of admission glucose and 30-day major adverse cardiovascular events on patients with chest pain in an emergency setting: insights from the China EMPACT registry

Yin,

Pan,

Zhang

et al. 2024

Front. Cardiovasc. Med.

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ObjectiveAlthough the association between admission glucose (AG) and major adverse cardiac events (MACE) is well-documented, its relationship with 30-day MACE in patients presenting with cardiac chest pain remains unclarified. In light of this, this study aims to examine the correlation between AG levels and the incidence of MACE in patients with chest pain in an emergency setting.Materials and methodsWe consecutively enrolled patients who presented to the emergency department for chest pain symptoms within 24 h from the EMPACT cohort in Eastern China (clinicaltrials.gov, Identifier: NCT02536677). The primary outcome was 30-day MACE, including all-cause death, recurrent myocardial infarction, urgent target vessel revascularization, stroke, cardiogenic shock, and cardiac arrest (CA). The associations of AG levels with 30-day MACE were analyzed using Kaplan–Meier analysis and Cox regression models.ResultsAmong 1,705 patients who were included in this study, 154 (9.03%) patients met the primary outcome at 30 days. The average age of the patients was 65.23 ± 12.66 years, with 1,028 (60.29%) being male and 500 (29.33%) having diabetes. The median AG levels were 7.60 mmol/L (interquartile range: 6.30–10.20). Kaplan–Meier survival analysis revealed significant differences in the 30-day MACE risk (P < 0.001 according to the log-rank test). We found that the highest AG level (Q4) was associated with increased MACE risk compared with the lowest AG level [adjusted hazard radio (aHR): 2.14; 95% confidence interval (CI): 1.2–3.815; P = 0.010]. In addition, Q4 level was also associated with increased all-cause death risk (aHR: 3.825; 95% CI: 1.613–9.07; P = 0.002) and increased CA risk (aHR: 3.14; 95% CI: 1.251–7.884; P = 0.015).ConclusionsAn elevated AG level significantly correlates with a higher incidence of 30-day MACE in patients with acute chest pain. The findings reveal the importance of managing AG levels to potentially reduce the risk of adverse cardiac events.

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Comparison of outcomes in emergency department patients with suspected cardiac chest pain: two-centre prospective observational study in Southern China

Cited by 3 publications

References 37 publications

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Chest Pain in Repeated Emergency Department Visitors

Impact of admission glucose and 30-day major adverse cardiovascular events on patients with chest pain in an emergency setting: insights from the China EMPACT registry

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