Comparison of ovarian induction outcome in Mongolian women classified by POSEIDON criteria

Abstract

Background Infertility has become a global issue, affecting 12.6–17.5% of women of reproductive age or 48.5 million couples. Infertility depends inversely on age, though, it is observed that young women are also now facing diminished ovarian reserve. Poor response to ovarian stimulation relates to the decreased ovarian reserve, and their remaining primordial, primary and secondary follicles have less sensitivity to Follicular stimulation hormone (FSH). The Patient-Oriented Strategy Encompassing Individualized Oocyte Number (POSEIDON) criteria have been proposed as a means to predict and plan the treatment of patients with poor ovarian responsiveness. Methods Here in, we report on implementation of the POSEIDON criteria for assessing ovarian response and compared assisted reproductive technology (ART) outcomes for women presenting with infertility at our clinic in Ulaanbaatar, Mongolia. Results The study included 158 women aged 23–45 years who were diagnosed with infertility. The participants’ mean age was 33.6 ± 5.3 years, their Body mass index (BMI) was 25.06 ± 3.86, and 88.0% (n = 139) of the patients were married. We evaluated the impact of the POSEIDON criteria on successful pregnancy by using logistic regression analysis. The probability of successful pregnancy is 2.2 times higher for POSEIDON group 1 and 2.3 times higher for group 2 compared to group 4. Conclusions The outcome of successful pregnancy can potentially be improved when assessing infertile Mongolian women and planning treatment by implementation of the use of the POSEIDON criteria.