Comparison of oxycodone and fentanyl for postoperative patient-controlled analgesia after orthopedic surgery

Lee, Dongwon; Kim, Eunju; Lee, Ji-hyang; Kim, Hyun; Son, Jong-chul

doi:10.17085/apm.2018.13.3.271

Cited by 2 publications

(2 citation statements)

References 31 publications

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“…Oxycodone for somatic pain such as pain after orthopedic surgery, the amount of oxycodone should be higher than the dose used for visceral pain. In a study of seventy-three patients undergoing orthopedic surgery randomly assigned to receive fentanyl or oxycodone using intravenous PCA, they concluded that with a 1:60 ratio of oxycodone to fentanyl in the application of PCA for pain control, the use of larger doses of oxycodone for 6 hours is effective in controlling early postoperative pain [72].…”

Section: Oxycodonementioning

confidence: 99%

Postoperative Pain in Orthopedics

Trinidad Castillo García,

Estela Elizabeth Ortega Ponce,

Carolina Martínez Esparza

2023

Topics in Postoperative Pain

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Most patients who undergo orthopedic surgery experience moderate-to-severe discomfort. Historically, opioids have been the primary medication class used to treat pain transmission pathways. In orthopedic practice, multimodal analgesia has become the predominant method of pain management. Utilizing multiple medications to treat post-surgical pain reduces the need for narcotics and accelerates the healing process. By introducing effective analgesic treatments and interventions, this procedure reduces the use of perioperative opioids and, over time, the risk of opioid toxicity and addiction. Previous research has demonstrated that multimodal analgesia reduces the use of analgesics in the early postoperative period for orthopedic procedures. Numerous substances can stimulate or sensitize directly. When the peripheral nociceptors are damaged, direct damage to the nervous system results in pain. Preoperative, intraoperative, and postoperative symptoms are essential. The emphasis is on management regimes and the pathophysiology underlying the mechanism for postoperative discomfort. A concise description of the effects of painkillers is provided. containing information on specific conditions and average dosage substances are classified further. Both neuropathy and subjective pain should be treated. By focusing on multimodal analgesia, anesthesiologists can reduce pain more effectively. More advanced techniques are utilized for postoperative pain management after orthopedic surgery, thereby enhancing the patient’s short- and long-term outcomes.

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Section: Oxycodonementioning

confidence: 99%

Postoperative Pain in Orthopedics

Trinidad Castillo García,

Estela Elizabeth Ortega Ponce,

Carolina Martínez Esparza

2023

Topics in Postoperative Pain

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“…Sedangkan, pasien dengan komorbid pada kelompok fentanil kontinu 19 orang, lebih tinggi dibandingkan dengan kelompok ketorolak intravena sebesar 5 orang. Namun demikian, penelitian ini berbeda dengan penelitian lain yang pemilihan jenis analgetik yang diberikan kepada pasien tidak bergantung pada komorbid atau penyakit lain yang dialami pasien 52,53,54 .…”

Section: Pendahuluanunclassified

Luaran Terapi Berdasarkan Jenis Pemberian Analgetik pada Pasien Pasca Operasi Ortopedi

Windari

Ikawati

Purwaningtyastuti

2020

J. Manaj. dan Pelayanan Farm.

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Postoperative pain was suffered by 80% of the total patients. One of the many surgical procedures performed is orthopedics. Ketorolac and fentanyl are often used for postoperative orthopedic pain. Appropriate postoperative pain management with adequate analgesic administration will accelerate pain reduction and shorten the patient's hospital stay. This study aims to determine the difference in the effect of continuous fentanyl and intravenous ketorolac on pain targets achievement and Length of Stay (LOS) of patients after orthopedic surgery. This study is a prospective cohort study, involving inpatients after orthopedic surgery in Dr. Sardjito Yogyakarta in July-October 2019. The independent variable is continuous fentanyl and intravenous ketorolac, while the dependent variable is the achievement of pain targets and LOS. The analysis was conducted by Fisher's exact test, Mann Whitney's test, and multivariate analysis to determine the dominance of variables on the research outcomes. There were 59 patients after orthopedic surgery in this study. A total of 34 patients in the continuous fentanyil group and 25 patients in the intravenous ketorolac group. There was no difference in the effect of continuous fentanyl administration and intravenous ketorolac on pain targets achievement (P = 0.711), while there were differences in the effect of continuous fentanyl administration and intravenous ketorolac on the average LOS of patients in the hospital (P = 0,000). Continuous fentanyl and intravenous ketorolac can both produce the achievement of adequate postoperative orthopedic pain targets, but the mean LOS becomes shorter in patients with intravenous ketorolac.

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Comparison of oxycodone and fentanyl for postoperative patient-controlled analgesia after orthopedic surgery

Cited by 2 publications

References 31 publications

Postoperative Pain in Orthopedics

Postoperative Pain in Orthopedics

Luaran Terapi Berdasarkan Jenis Pemberian Analgetik pada Pasien Pasca Operasi Ortopedi

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