Comparison of Peak Expiratory Flow Variability Between Workers With Work-Exacerbated Asthma and Occupational Asthma

New-onset adult asthma in relation to damp and moldy workplaces

“…Increases in bronchial hyperreactivity (Newman Taylor et al 2004) or exhaled nitric oxide (Lemiere 2007) over an exposure period may be a way to improve the reliability of PEF recording. While serial PEF records do demonstrate the association with work, the major weakness is that they do not accurately diVerentiate between work-exacerbated asthma and OA (Chiry et al 2007). For diagnosing OA, other aspects, like disease history and immunological assessment, have to be included.…”

Work-Related Asthma in Automobile Spray Painters: Two Case Reports

“…Commonly performed in routine practice are the "stop-resume" work tests using serial measurements of PEFR, NSBH and/or sputum eosinophilia (26,29). As Chiry et al (29) reported that in some cases serial PEFR measurement failed to distinguish allergic OA from WEA, and indicated a need of additional tests, such as changes in airway responsiveness and immunologic tests, we reassessed the work-relatedness of asthma in our cases by serial bronchoprovocation testing. Similar to our previous study (30), in both cases the results of the two methods repeated each other, confirming the conclusion of Côté et al (31) that the combination of serial PEFR measurement with serial measurement of NSBH does not add anything in differentiation between allergic OA and WEA to monitoring by PEFR alone.…”

“…When performed in a laboratory, the challenge is controlled, but also artificial (24,28). Commonly performed in routine practice are the "stop-resume" work tests using serial measurements of PEFR, NSBH and/or sputum eosinophilia (26,29). As Chiry et al (29) reported that in some cases serial PEFR measurement failed to distinguish allergic OA from WEA, and indicated a need of additional tests, such as changes in airway responsiveness and immunologic tests, we reassessed the work-relatedness of asthma in our cases by serial bronchoprovocation testing.…”

Pulmonary manifestations of polyvinyl chloride exposure

“…Ardından tüm çalışanlar bir ay süreyle iş ortamında bir kez işe başlamadan önce, iki kez iş döneminde ve bir kez de işten çıkmadan hemen önce olmak üzere günde toplam dört kez PEF öl-çümü yaptılar. PEF takibi yapılan işçilerdeki günlük PEF değişkenlikleri iki ayrı metotla (en yüksek-en dü-şük/en yüksek x 100) ve (en yüksek-en düşük/ortalama x 100) hesaplandı (11).…”