Comparison of pediatric end-tidal CO2 measured with nasal/oral cannula circuit and capillary Pco2

Abramo, Thomas J.; Cowan, Michael R; Scott, S. M.; Primm, Patricia A.; Wiebe, Robert A.; Signs, Marla

doi:10.1016/0735-6757(95)90236-8

Cited by 22 publications

(14 citation statements)

References 12 publications

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“…4,5 The remaining 4 studies were confined to a pediatric population, 6-9 3 of which evaluated specific pediatric populations with normal lung function. 6,8,9 The fourth study, which examined children with both upper and lower airway disease, showed good concordance between arterial partial pressure of carbon dioxide (PaCO 2 ) and PetCO 2 . 7 Consequently, in adult asthmatic patients with compromised pulmonary function, the extent of agreement between PetCO 2 and PaCO 2 remains unclear.…”

Section: Introductionmentioning

confidence: 96%

“…2 Despite a clearly identified need for further clinical investigation to define the role of capnography in emergency care, 3 we could find only 6 relevant studies in the English emergency medicine literature. [4][5][6][7][8][9] The first 2 investigations examined small, heterogeneous cohorts of healthy patients, of whom few had pulmonary disease. 4,5 The remaining 4 studies were confined to a pediatric population, 6-9 3 of which evaluated specific pediatric populations with normal lung function.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Concordance Between Capnography and Arterial Blood Gas Measurements of Carbon Dioxide in Acute Asthma

Corbo

Bijur

Lahn

et al. 2005

Annals of Emergency Medicine

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Section: Introductionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

Concordance Between Capnography and Arterial Blood Gas Measurements of Carbon Dioxide in Acute Asthma

Corbo

Bijur

Lahn

et al. 2005

Annals of Emergency Medicine

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“…10,11 The mean difference between EtCO 2 values and capillary CO 2 values in healthy children was 1.96 mm Hg (95% CI = À3.3 to 7.2 mm Hg). In children with respiratory disease, the mean difference was 3.2 mm Hg (95% CI = À1.6 to 8.0 mm Hg).…”

Section: Discussionmentioning

confidence: 99%

“…The oral-nasal cannula is better tolerated, would be easy to use in routine clinical practice, and is similar technology to that used in the study by Abramo et al comparing EtCO 2 values with capillary CO 2 values. 10 The oral-nasal cannula is designed for use with the higher respiratory rates and lower tidal volumes of children, in addition to accommodating both nose and mouth breathing. We are not aware of any published data directly comparing EtCO 2 measurements taken with oral-nasal cannulas versus mouthpiece/nose clip devices.…”

Section: Discussionmentioning

confidence: 99%

“…EtCO 2 values have been shown to be a reliable measurement of ventilatory status in both healthy children and those with respiratory diseases. 10,11 No study has rigorously examined its use in the evaluation and management of children with acute exacerbations of asthma, and data describing the association between EtCO 2 values and other measures of asthma severity are lacking.…”

mentioning

confidence: 99%

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End-tidal Carbon Dioxide Measurements in Children with Acute Asthma

2007

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Objectives: A noninvasive method to assess ventilation may aid in management of children with acute asthma. The purpose of this study was to evaluate the association between end-tidal carbon dioxide (EtCO 2 ) values and disease severity among children with acute asthma.Methods: This was a prospective, blinded, observational study of children 3-17 years old treated for acute asthma in a pediatric emergency department (ED). EtCO 2 measurements were taken before the initiation of therapy and after each nebulization treatment (maximum of three). Peak expiratory flow rate (PEFR), Pediatric Asthma Severity Score (PASS), oxygen saturation, and disposition were recorded. Treating physicians, unaware of the EtCO 2 results, made all treatment decisions, including disposition.Results: One hundred children were enrolled. The mean initial EtCO 2 value was 35 mm Hg (95% confidence interval = 34.3 to 36

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Bias between capnometry and venous carbon dioxide during initial assessment of pediatric emergency department patients: A video‐based study

Stratton,

Overmann,

Zhang

et al. 2024

JACEP Open

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ObjectiveThe bias of capnometry (ETCO2) and venous carbon dioxide (vpCO2) among pediatric emergency department (PED) patients triaged to critical care areas is unknown. We aimed to explore correlations and bias between ETCO2 and vpCO2¸and identify predictors of bias.MethodsThis was an observational, video‐based, retrospective study comparing ETCO2 and vpCO2. Pediatric patients with simultaneous ETCO2 and vpCO2 data were included. Our primary aim utilized linear regressions to determine correlations and Bland–Altman analysis to assess bias. Our secondary aim utilized multiple regression to identify clinical covariates contributing to bias. Covariates included age, respiratory rate, heart rate, mean arterial blood pressure, capnometry interface, PED diagnosis, and PED disposition.ResultsA total of 200 PED patients with ETCO2 and vpCO2 data were included. The median (interquartile range [IQR]) ETCO2, vpCO2, and ΔCO2 in mmHg were 38 (32, 46), 49 (41, 61), and 11 (4, 20), respectively. ETCO2 (r = 0.76) and ΔCO2 (r = 0.71) were highly correlated with vpCO2. The mean bias between ETCO2 and vpCO2 was −14.1 mmHg (95% confidence interval [CI], −41.9 −13.7). The bias between ETCO2 and vpCO2 increased at higher values of each measure. ETCO2 sampling interface was the only independent predictor of vpCO2 in our multivariate analysis. Patients requiring bag‐valve mask (BVM) ventilation had the highest median bias between ETCO2 and vpCO2 (29 mmHg, IQR 15, 37).ConclusionETCO2 and vpCO2 were highly correlated. However, bias increased at higher levels of both ETCO2 and vpCO2. Among PED patients, ETCO2’s ability to approximate vpCO2 diminishes with worsening hypercarbic respiratory failure.

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Comparison of pediatric end-tidal CO2 measured with nasal/oral cannula circuit and capillary Pco2

Cited by 22 publications

References 12 publications

Concordance Between Capnography and Arterial Blood Gas Measurements of Carbon Dioxide in Acute Asthma

Concordance Between Capnography and Arterial Blood Gas Measurements of Carbon Dioxide in Acute Asthma

End-tidal Carbon Dioxide Measurements in Children with Acute Asthma

Bias between capnometry and venous carbon dioxide during initial assessment of pediatric emergency department patients: A video‐based study

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