Comparison of Percutaneous Coronary Intervention Outcomes in Men and Women Using the Transradial Approach in Acute Coronary Syndrome

Dall'Orto, Clarissa Campo; Lopes, Rubens Pierry Ferreira; Filho, Gilvan Vilella Pinto; Santos, Thayná Soares; Cisari, Giovanni; Perea, Julio Cesar Castilho; Costa, Guilherme de Oliveira Silveira

doi:10.1016/s0104-1843(14)50005-7

Cited by 2 publications

(5 citation statements)

References 16 publications

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“…There were 1 registry-based RCT, 7 3 post hoc analyses of RCTs, [8][9][10] and 11 observational studies. [11][12][13][14][15][16][17][18][19][20][21] All of these studies recruited patients with acute coronary syndrome (ACS), whereas 9 studies enrolled patients with non-ACS as well. 7,9,11,14,15,[17][18][19][20] Transradial PCI was used in 283 121 (10.7%) of 2 650 885 males and in 105 643 (8.3%) of 1 270 973 females.…”

Section: Resultsmentioning

confidence: 99%

“…When comparing sex-specific mortality from 6 studies 9,11,12,14,19,20 involving 114 600 women and 325 073 men, there was a significantly higher all-cause mortality rate in women (2.1%) than men (1.4%) regardless of the vascular access (OR 1.45, 95% CI: 1.38-1.52). The crude ORs were in accordance with the adjusted OR (Supplemental Table 3).…”

Section: All-cause Deathmentioning

confidence: 99%

“…Meta-analysis of these data demonstrated TRI-versus-TFI ORs of 0.37 (95% confidence interval [CI]: 0.29-0.46) and 0.47 (95% CI: 0.40-0.55; interaction P ¼ .07) in favor of the TRI group for women and men, respectively (Figure 2A). Nine studies 8,9,11,12,14,15,17,19 reported the sex-specific bleeding complications. Figure 2B shows women have higher incidence of bleeding complications (7.0%) than men (3.5%; OR: 2.17, 95% CI: 1.97-2.40).…”

Section: Bleeding Complicationsmentioning

confidence: 99%

“…Whereas, the crossover rate was identical between females (2.0%) and males (2.0%) when using TFI (OR 1.00, 95% CI:0.59-1.70; interaction P ¼ .05; Supplemental Figure 2B). Sex-specific data on fluoroscopy time were available from only 2 studies 8,12 with 1926 women and 5283 men. Although TRI had longer fluoroscopy time, the fluoroscopy time did not differ between males and females in the two vascular accesses (interaction P ¼ 1.00; Supplemental Figure 3).…”

Section: Gender Difference In Operation-related Indicatorsmentioning

confidence: 99%

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Gender Disparity in the Safety and Efficacy of Radial and Femoral Access for Coronary Intervention

Huang

Wang

et al. 2016

Angiology

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Our aim was to investigate the gender disparity in the safety and efficacy of transradial percutaneous coronary intervention (PCI; TRI) and transfemoral PCI (TFI) by a meta-analysis. MEDLINE, Embase, and CENTRAL were searched to identify studies on vascular access with sex-specific events available or studies on sex difference with the events reported by vascular access. Fifteen studies involving 3 921 848 participants were included. Transradial PCI significantly reduced the risk of bleeding complications in both sexes (TRI-versus-TFI odds ratio [OR]: 0.37 in females vs 0.47 in males) and major adverse cardiac events (MACE) in females (OR: 0.70, P < .001) but not in males (OR: 0.83, P = .15) compared to TFI. Transradial PCI diminished the sex difference in the incidence of bleeding complications (female-versus-male OR: 1.82 with TRI vs 2.39 with TFI; interaction P = .01) and MACE (female-versus-male OR: 1.21 with TRI vs 1.41 with TFI; interaction P = .003) compared to TFI. Females were associated with higher crossover rate in the TRI subgroup but not in the TFI subgroup (interaction P = .05). In conclusion, TRI may improve the safety and efficacy of outcomes in both sexes and be an effective means to cut down the gender difference in prognosis.

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Section: Resultsmentioning

confidence: 99%

Section: All-cause Deathmentioning

confidence: 99%

Section: Bleeding Complicationsmentioning

confidence: 99%

Section: Gender Difference In Operation-related Indicatorsmentioning

confidence: 99%

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Gender Disparity in the Safety and Efficacy of Radial and Femoral Access for Coronary Intervention

Huang

Wang

et al. 2016

Angiology

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“…The Dall'Orto et al [10] research found that deaths in hospitals (5.8% against 5.5%; p = 0.81), myocardial infarction (1.4% against 0; p = 0.76), and urgent PCI were comparable across groups (1.4% vs 0; p = 0.76). In the women's groups, there was one incidence of subacute stent thrombosis with the accompanying increase in myocardial infarction and immediate percutaneous reaction in the ST sector.…”

Section: Discussionmentioning

confidence: 97%

Comparison between Trans-Radial Versus Trans-Femoral Arterial Access in Primary Percutaneous Coronary Intervention

Elrabbat

Hamoda

Elnagar

et al. 2021

Benha Journal of Applied Sciences

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Background: Coronary catheterization is usually performed via the trans-femoral approach. Trans-radial access offers advantages in comparison with trans-femoral access, especially under conditions of aggressive anticoagulation and antiplatelet treatment in which bleeding complications at the femoral puncture site can result in increased morbidity and duration of hospitalization, Aim and objectives: the aim of the study was to compare 30 days outcome between radial and femoral approaches in patients presenting with ST-segment elevation myocardial infarction (STEMI) and undergoing primary percutaneous coronary intervention (PCI), Subjects and methods: this was a Prospective, randomized, open-label, double-arm, single center study, that was conducted on 120 STEMI patients; subdivided randomly into 2 groups. Group A (60 patients) had Primary PCI through femoral access; Group B (60 patients) had Primary PCI through radial access, Results: Hospitalization time in group (I) was ranged between 3-8 days with mean± S.D. 5.35±1.686 days while in group (II) was ranged between 5-10 days with mean± S.D. 7.32±1.751 days. There were statistically significant differences between groups, and Complications in group (I) showed that 9(15.0%) had access site complication, 4(6.7%) had hematoma, 2(3.3%) had Pseudoaneurysm and 7(11.7%) had Radial artery spasm while in group (II) 6(10.0%) had Access site complication. There was no statistically significant difference between groups, Conclusion: trans-radial approach is an equally effective approach as trans-femoral approach similar success and complication rates.

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Comparison of Percutaneous Coronary Intervention Outcomes in Men and Women Using the Transradial Approach in Acute Coronary Syndrome

Cited by 2 publications

References 16 publications

Gender Disparity in the Safety and Efficacy of Radial and Femoral Access for Coronary Intervention

Gender Disparity in the Safety and Efficacy of Radial and Femoral Access for Coronary Intervention

Comparison between Trans-Radial Versus Trans-Femoral Arterial Access in Primary Percutaneous Coronary Intervention

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