Comparison of performance and intestinal morphology of broilers using step-down supplementation with a mannan-rich fraction versus bacitracin methylene disalicylate

Abstract

Two experiments were conducted to compare effects of utilising step-down dosing of a mannan-rich fraction (MRF) of yeast cell wall or the antimicrobial growth promoter (AGP) bacitracin methylene disalicylate (BMD) when chicks were raised on built-up litter. Chicks were randomly assigned to one of three treatment groups (12 pen replicates; 50 birds per pen): basal diet (control) or basal diet plus MRF (Actigen™; Alltech Inc., Nicholasville, KY) or BMD (Alpharma Inc., Fort Lee, NJ). In experiment two, intestinal morphology and litter scores were determined on d 42. In experiment one, MRF and BMD increased BW gain at d 21 and d 42 compared with control (P ≤ 0.05) and d 42 BW was greater in BMD birds than controls (P ≤ 0.05). Adjusted FCRs were lower in MRF and BMD birds from d 0 to d 42 (P = 0.06). In experiment two, there was no effect of treatment on d 21 BW, but MRF and BMD improved adjusted FCR (P = 0.02) compared with control. By d 35, both MRF and BMD birds had greater BWs than controls (P = 0.04). At d 42, MRF-supplemented birds had greater BW than controls (P ≤ 0.05). D 35 and d 42 FCR improved with MRF or BMD compared with control (P ≤ 0.01). Litter conditions improved (P ≤ 0.05) when birds were fed diets with BMD and MRF compared with control-fed birds. Jejunal morphology, including villi height (P ≤ 0.05), villi height: crypt depth ratio (P ≤ 0.05), and goblet cell numbers (P ≤ 0.05) improved with MRF and BMD compared with control. Both MRF and BMD improved broiler performance, potentially related to the improvements observed in intestinal morphology. In conclusion, step-down supplementation with MRF may offer a potential alternative to AGP to improve performance in broilers raised in commercial settings.

Growth performance, serum blood biochemistry, and intestinal properties of Arbor Acres Broiler fed diets containing mannan-riched fraction (MRF) and probiotic-enhanced liquid acidifier

“…The combination of MRF and probiotic helps the treatment (T3) in blood and increase body weight gain of broilers. Compared with Brennan et al (2014) stated the used of MRF give significant difference (P<0.05) on body weight gain at 21 d and 35 d compared than control (877 g (MRF 400 g/ton (21 d); 50 g/tonne (35d)) vs 819 g control) due it combination both of mannan and probiotic. The result according to the table 2 got additional statement from Brennan et al (2014) stated that the result of performance broiler were according due to factor rearing condition, the broiler will increase the body weight gain when the environment (bedding are clean) (Brennan et al, 2014).…”

“…The result may be correlated with the treatment of probiotics, and prebiotics that had helped to increase the surface area of the morphology of small intestine (jejunum). Compared Brennan et al, (2014) The used of MRF 7 d to 21 (400 g/tonne); 21 to 42 d (200 g/tonne) better than control (1267.3 vs 796.6) increase villus height of broiler (P<0.05), villus height in jejunum tissue increase is a positive indicator of intestinal health and increased of absorptive area F. The level addition of a probiotic to broiler increased the villus height leading to increased intestinal surface area and therefore to increased digestion and absorption of nutrients in the basal diet (Brennan et al, 2014). The result (table 8) The treatment (T3) give the greater compared to all treatment and control (718.50 vs 713.75 (T1), 695.50 (T2), and 598.50 (control) µm; villus height).…”

Antibiotics in broilers chicken production: a review of impacts, challenges and potential alternatives

“…The addition of various levels of MOS to the broiler diets significantly increased their body weight and improved feed conversion efficiency (Benites et al, 2008;Bozkurt et al, 2008). They have the ability to increase intestinal villi height (Baurhoo et al, 2007), enhanced immunity (Shanmugasundaram and Selvaraj, 2012), influence jejunal gene expression and intestinal microbiota (Brennan et al, 2013;Pourabedin et al, 2014). Benites et al (2008) evaluated the effects of dietary mannan oligosaccharide (Bio-Mos and SAF-Mannan) on growth performance on broiler chickens and found that chickens on Bio-Mos at 1.0/0.5/0.5 (starter/ grower/finisher) kg/ton diets had significantly greater body weight at day 42 than birds fed control or SAF-Mannan-supplemented diets.…”