Comparison of PG-SGA, SGA and body-composition measurement in detecting malnutrition among newly diagnosed lung cancer patients in stage IIIB/IV and benign conditions

Abstract

Assessment tools and body-composition measurements are useful in diagnosing malnutrition. Which one is better for lung disease patients is unclear. The objectives of the present study are: to assess relationships between different methods of nutritional measurements in lung diseases patients; to determine which one is better in diagnosing malnutrition for lung disease patients; and to determine whether lung cancer patients can be differentiated from benign lung disease patients using different measurements. A total of 96 newly diagnosed primary lung cancer patients in stage IIIB/IV and 52 benign lung disease patients nutritional status were assessed according to the SGA, the scored PG-SGA, and serum albumin, prealbumin, transferrin, hemoglobin, total lymphocyte count, body mass index (BMI), and weight. A total of 40% of lung cancer patients were severely malnourished, with men or elder having a higher rate of malnutrition. Significantly lower values of weight, BMI, total lymphocyte count, transferrin, prealbumin and serum albumin were found for them. Age, sex, weight, weight half year ago and prealbumin are in the regression equation to predict them. For benign lung disease patients, 21.2% were severely malnourished with significantly lower values of weight and transferrin. Age and prealbumin are in the equation to predict severely malnourished benign lung disease patients. The highest receiver operation characteristic area under the curve was found for the PG-SGA score, BMI and weight. PG-SGA global rating, age and iron-transferring protein are in the equation for predicting disease status. The SGA and PG-SGA are appropriate for identifying malnutrition in lung disease patients. Lung cancer patients can be differentiated from benign conditions by PG-SGA.

Bioelectrical impedance analysis for monitoring cancer patients receiving chemotherapy and home parenteral nutrition

“…Subjective assessment of nutritional status is commonly used to supplement objective measures, and PG-SGA has been shown to be effective in assessing nutritional status in cancer patients [ 49 , 50 ]. At the initiation of the study, all patients were rated as moderately to severely malnourished.…”

Severe malnutrition evaluated by patient-generated subjective global assessment results in poor outcome among adult patients with acute leukemia

“…Previous studies have showed that the influence of BMI on survival time differs from each other, [ 5 – 9 ] and other indexes such as weight and albumin are also unstable. [ 10 ] PG-SGA is highly recommended by nutritionists and can be easily applied in leukemia patients. Thus, we aimed to evaluate the nutritional status of adult patients with AL using PG-SGA and to investigate the influence of nutritional status on prognosis.…”

“…[ 3 , 4 ] Various nutritional evaluation tools such as body mass index (BMI), weight loss, biochemical indexes, and body composition are applied in different studies, yielding inconsistent results. [ 5 – 10 ] This situation is a main factor limiting leukemia-related nutritional research.…”

Diagnostic work-up for the detection of malnutrition in hospitalized cancer patients

“…Other trials have been limited to patients with a particular entity, for example patients with lung cancer. 35…”