“…Several studies have shown that fewer infl ammatory cells and pigments are deposited on HSM IOLs than on non-HSM IOLs and that the early postoperative anterior chamber reaction of HSM IOLs is less than that of non-HSM IOLs. [3][4][5] It is postulated that the HSM IOL, which has a hydrophilic surface, leads to a reduction Jpn Abstract Purpose: To compare posterior capsular opacifi cation (PCO) in a heparin-surface-modifi ed (HSM) hydrophilic acrylic intraocular lens (IOL) and a hydrophobic acrylic IOL.Methods: Seventy-eight patients with simple cataract were randomized to receive either the BioVue 3 HSM hydrophilic acrylic IOL (Ophthalmic Innovations International, Ontario, CA, USA) (n = 38) or the Sensar AR40e hydrophobic acrylic IOL (AMO, Santa Ana, CA, USA) (n = 40). Another 99 patients with complicated cataract received either the BioVue 3 (n = 49) or the Sensar AR40e IOL (n = 50).…”