2023
DOI: 10.1186/s12871-023-02091-3
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Comparison of postoperative nausea and vomiting between Remimazolam and Propofol in Patients undergoing oral and maxillofacial surgery: a prospective Randomized Controlled Trial

Abstract: Background Remimazolam is a recently approved, ultra-short-acting benzodiazepine. However, few studies have investigated remimazolam in relation to postoperative nausea and vomiting (PONV). This study aimed to compare the effects of remimazolam and propofol on PONV in patients undergoing oral and maxillofacial surgery. Methods Patients (n = 206) aged 19–65 years who were scheduled for oral and maxillofacial surgery were randomized into two groups, … Show more

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Cited by 10 publications
(9 citation statements)
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“…To the best of our knowledge, few studies have compared the incidence of PONV between remimazolam and other intravenous anesthetics. According to Kim et al [ 28 ], there was no significant difference in the incidence and the severity of PONV between using remimazolam and propofol as intravenous anesthetics. Further studies will need to be conducted to justify the usefulness of remimazolam in reducing the incidence of PONV compared to other anesthetics.…”
Section: Discussionmentioning
confidence: 99%
“…To the best of our knowledge, few studies have compared the incidence of PONV between remimazolam and other intravenous anesthetics. According to Kim et al [ 28 ], there was no significant difference in the incidence and the severity of PONV between using remimazolam and propofol as intravenous anesthetics. Further studies will need to be conducted to justify the usefulness of remimazolam in reducing the incidence of PONV compared to other anesthetics.…”
Section: Discussionmentioning
confidence: 99%
“…Upon reviewing the full-text articles of the remaining records, we excluded 13 studies for various reasons: they were not randomized controlled trials [32][33][34][35][36][37], did not set up a propofol group [38,39], did not have routine flumazenil usage in the remimazolam group [19,[40][41][42], or did not have outcomes we wanted [43]. Ultimately, nine studies meeting the criteria were included [44][45][46][47][48][49][50][51][52]. The selection process is illustrated in Figure 1.…”
Section: Search and Selectionmentioning
confidence: 99%
“…set up a propofol group [38,39], did not have routine flumazenil usage in the remimazolam group [19,[40][41][42], or did not have outcomes we wanted [43]. Ultimately, nine studies meeting the criteria were included [44][45][46][47][48][49][50][51][52]. The selection process is illustrated in Figure 1.…”
Section: Search and Selectionmentioning
confidence: 99%
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