Comparison of pre- and post-hemodialysis PHQ-9 depression scores in patients with end-stage renal disease: A cross-sectional study

AlAwwa, Izzat; Ibrahim, Sarah; Obeid, Ahmad; Alfraihat, Nadeen; Al-Hindi, Reham; Jallad, Shatha; Al-Awwa, Ahmad

doi:10.1177/0091217420973489

Cited by 4 publications

(6 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The findings reveal a notable depression prevalence of 63% among HD patients in Hodeida city, as determined by the PHQ-9 scale. While this prevalence is lower than the prevalence reported in China (73.8%) 32 but higher than that reported in Jordan (48.5%), 13 where both studies utilized the same scale. Other smaller-scale studies in Saudi Arabia and Lebanon reported lower prevalence rates of 24.6% and 40.8%, respectively, using the Hospital Anxiety and Depression Scale.…”

Section: Discussioncontrasting

confidence: 64%

“…The severity of depression was categorized based on the total score as none (0–4), mild (5–9), moderate (10–14), moderately severe (15–19), and severe (20–27). 13 , 27 In this study, the cutoff score of PHQ-9 was set at a total score of 10 and higher to identify patients with moderate or severe depression because its sensitivity and specificity were best balanced at this cutoff point, as revealed in previous studies. 23 , 28 …”

Section: Methodsmentioning

confidence: 99%

“…A prospective cohort study involving 462,293 Taiwanese adults revealed that patients with CKD had 83% a higher mortality rate for all causes and 100% higher rate for cardiovascular disease. 11 The diagnose of depression in ESRD patients is challenging due to the overlap of the main somatic symptoms of the depression, such as anorexia, fatigue and sleep disturbances, with those of ESRD, 12 , 13 leading to delays in diagnosis and treatment. 14 Early and appropriate diagnosis of depression in ESRD patients is crucial for improving treatment adherence and quality of life.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Prevalence of Depression and Its Associated Factors Among Hemodialysis Patients in Hodeida City, Yemen

Alkubati,

Al-Sayaghi,

Salameh

et al. 2024

JMDH

View full text Add to dashboard Cite

Background Depression has a negative impact on the health outcomes of hemodialysis (HD) patients, including decreased quality of life and increased morbidity and mortality rates. Therefore, this study aimed to determine the prevalence of depression and its associated factors among HD patients in Hodeida city, Yemen. Methods A cross-sectional study involving 200 HD patients at the Dialysis Center in Hodeida was conducted from February to May 2022. Data on depression were collected using the 9-item Patient Health Questionnaire (PHQ-9). Association of sociodemographic characteristics of patients with depression were assessed using chi-square, subsequently by multivariable logistic regression. Statistical significance was set at P -values <0.05. Results The response rate was 98% (200/204). Depression was prevalent among 63% of HD patients at the Dialysis Center in Hodeida city. Sex was significantly associated with depression, where female patients were more frequently depressed than males (82.4% vs 56.4%, P < 0.001). In addition, employment status and medical insurance were significantly associated with depression, where unemployed patients were more frequently depressed than employed patients (67.6% vs 52.5%, P = 0.041) and patients with medical insurance were less frequently depressed than their counterparts (47.1% vs 66.3%, P = 0.035). Conclusion Depression is highly prevalent among HD patients in Hodeida city. Female sex, unemployment and lack of medical insurance are predictors of depression among HD patients. These findings emphasize the urgent need for targeted interventions. Implications for practice Depression is common among HD patients, so that, psychiatric physicians and nurses are increasingly needed in HD centers to implement mental health assessment of patients for depression signs and symptoms to help in early diagnosis and management of depression in order to improve patients’ quality of life and preventing negative outcomes.

show abstract

Section: Discussioncontrasting

confidence: 64%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence of Depression and Its Associated Factors Among Hemodialysis Patients in Hodeida City, Yemen

Alkubati,

Al-Sayaghi,

Salameh

et al. 2024

JMDH

View full text Add to dashboard Cite

show abstract

“…AlAwwa et al ( 34 ) demonstrate that hemodialysis may not be associated with a greater or lesser presence of depressive symptoms. However, by including only patients on hemodialysis, our study aimed to homogenize the population studied and, mainly, to identify the influence of depression on the functional capacity and quality of life of patients with ESRD.…”

Section: Discussionmentioning

confidence: 99%

“…The prevalence of depression in this population is well known (34,35). In a cross-sectional study, more than 66% of the evaluated patients had depressive disorders.…”

Section: Discussionmentioning

confidence: 99%

Quality of life and functional capacity in depressive patients on hemodialysis: a systematic review and meta-analysis

Moreira,

Cavalli,

Righi

et al. 2023

Braz J Med Biol Res

View full text Add to dashboard Cite

Depression is a common disorder in patients with chronic kidney disease (CKD), and some data support its relationship with functional capacity and quality of life. However, to date, this has not been evaluated systematically or through meta-analysis. We sought to investigate the relationship of quality of life and functional capacity with depressive disorder in patients with CKD on hemodialysis. This systematic review considered studies published up to 2021 and included cross-sectional and cohort studies. PubMed, Embase, SPORTDiscus, Web of Science, and Cochrane (CENTRAL) databases were used to search for studies. The New Castle-Ottawa Quality Assessment scale was used to measure the quality of the studies. A total of 4,626 studies were found and, after applying the selection criteria, 16 studies (2,175 patients) remained for qualitative analysis and 10 for meta-analysis (1,484 patients). The physical component summary (MD=-6.563; 95%CI: −9.702 to −3.424) and mental component summary (MD=-18.760; 95%CI: −28.641 to −8.879) were lower in depressive patients, as in all Short Form Health Survey 36 (SF-36) domains. Only one study provided data regarding functional capacity, but it was not evaluated by the defined outcome measure. Twelve studies were classified as “moderate quality” (5 to 6 stars) and four were classified as “low-quality” (0 to 4 stars). This meta-analysis with CKD patients on hemodialysis showed a negative relationship between depression and quality of life, with worsening in all physical and mental domains of the SF-36 in depressed patients.

show abstract

Using latent variables to improve the management of depression among hemodialysis patients

Gunzler,

Dolata,

Figueroa

et al. 2024

Renal Failure

View full text Add to dashboard Cite

Background Screening for depression can be challenging among hemodialysis patients due to the overlap of depressive symptoms with dialysis or kidney disease related symptoms. The aim of this study was to understand these overlapping symptoms and develop a depression screening tool for better clinical assessment of depressive symptoms in dialysis patients. Methods We surveyed 1,085 dialysis patients between March 1, 2018 and February 28, 2023 at 15 dialysis facilities in Northeast Ohio with the 9-item patient health questionnaire (PHQ-9) and kidney disease quality of life (KDQOL) instrument. To evaluate overlap across questionnaire items, we used structural equation modeling (SEM). We predicted and transformed factor scores to create a hemodialysis-adjusted PHQ-9 (hdPHQ-9). In exploratory analysis ( N = 173), we evaluated the performance of the hdPHQ-9 relative to the PHQ-9 that also received a Mini-International Neuropsychiatric Interview. Results Our study sample included a high percentage of Black patients (74.6%) and 157 (14.5%) survey participants screened positive for depression (PHQ-9 ≥ 10). The magnitude of overlap was small for (respectively, PHQ-9 item with KDQOL TM item) fatigue with washed out, guilt with burden on family, appetite with nausea and movement with lightheaded. The hdPHQ-9 showed reasonably high sensitivity (0.81 with 95% confidence interval [CI] 0.58, 0.95) and specificity (0.84 with 95% CI 0.77, 0.89); however, this was not a significant improvement from the PHQ-9. Conclusion There is little overlap between depressive symptoms and dialysis or kidney disease symptoms. The PHQ-9 was found to be an appropriate depression screening instrument for dialysis patients.

show abstract

Comparison of pre- and post-hemodialysis PHQ-9 depression scores in patients with end-stage renal disease: A cross-sectional study

Cited by 4 publications

References 19 publications

Prevalence of Depression and Its Associated Factors Among Hemodialysis Patients in Hodeida City, Yemen

Prevalence of Depression and Its Associated Factors Among Hemodialysis Patients in Hodeida City, Yemen

Quality of life and functional capacity in depressive patients on hemodialysis: a systematic review and meta-analysis

Using latent variables to improve the management of depression among hemodialysis patients

Contact Info

Product

Resources

About