Comparison of pregnancy outcomes in women with hypertensive disorders of pregnancy using 24‐hour urinary protein and urinary microalbumin to creatinine ratio

Gangaram, Rajesh; Naicker, Manogaran; Moodley, Jagidesa

doi:10.1016/j.ijgo.2009.05.023

Cited by 19 publications

(13 citation statements)

References 11 publications

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“…compared the diagnostic value of the micro ACR with that of the 24-h urine protein test when screening for proteinuria among pregnant women with hypertension. [ 14 ] They reported that the value of the two tests in this context was the same and concluded that measurement of the micro ACR may be a good substitute for a random urine protein test. In the present study comparison of ACR with 24-h urinary protein was not done.…”

Section: Discussionmentioning

confidence: 99%

Comparison of obstetric outcome in pregnant women with and without microalbuminuria

et al. 2015

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Background:Maternal and neonatal outcome is an index of quality of health and life in human society. To predict serious outcomes in pregnancy various parameters are being researched so that pregnant women who are at risk are identified early and measures taken to ensure a good outcome of pregnancy. Studies have shown an association between microalbuminuria and adverse pregnancy outcome. This study was undertaken to compare obstetric outcome in pregnant women with and without microalbuminuria.Materials and Methods:A prospective cohort study was performed on 69 pregnant women between 20 and 28 weeks of gestation. Urine tests for albuminuria and creatinine measurements were performed in all women and the albumin to creatinine ratio was calculated. The women with microalbuminuria and those without microalbuminuria were monitored until the end of their pregnancy and compared for pregnancy outcome.Results:The age distribution in the two groups was found to be similar and comparable. Preterm labor was strongly associated with microalbuminuria group (P = 0.001**)strongly significant. Incidence of maternal complications were more with microalbuminuria group (P < 0.001**). Fetal complications were significantly more in terms of intrauterine growth restriction, prematurity, low birth weight, low Apgar score and more incidence of neonatal intensive care unit admission with microalbuminuria group (P = 0.010*)moderately significant.Conclusion:It was found that fetal complications were more associated with babies of pregnant women with microalbuminuria. Though maternal complications were more associated with microalbuminuria group, individual events like premature rupture of membrane, preterm premature rupture of membrane had no statistically significant association with microalbuminuria except preterm labor. However, occurrence of pre-eclampsia was more with microalbuminuria, though it didn’t carry any statistical significance.

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Section: Discussionmentioning

confidence: 99%

Comparison of obstetric outcome in pregnant women with and without microalbuminuria

et al. 2015

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“…Gangaram et al [17] compared the diagnostic value of the microalbumin to creatinine ratio with that of the 24‐hour urine protein test when screening for proteinuria among pregnant women with hypertension [17]. They reported that the value of the 2 tests in this context was the same and concluded that measurement of the microalbumin to creatinine ratio may be a good substitute for a random urine protein test.…”

Section: Discussionmentioning

confidence: 99%

Comparison of pregnancy outcome among nulliparas with and without microalbuminuria at the end of the second trimester

Bahasadri

Kashanian

Khosravi

2011

Intl J Gynecology & Obste

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“…Four of the studies used 24 h urine protein as the reference standard and one used adverse pregnancy outcome [6]. Of the four studies that used 24 h collection as the reference standard, two were in a hypertensive population and two were in a population with hypertension and proteinuria on dipstick.…”

Section: Discussionmentioning

confidence: 99%

“…The performance of uACR to predict proteinuria varied widely. Gangaram et al [6] reported results for adverse outcome, including maternal morbidity, for which the sensitivity was 0.55 (CI: 0.23 to 0.83) and specificity was 0.57 (CI: 0.48 to 0.65), and perinatal death, for which the sensitivity was 0.82 (CI: 0.48 to 0.98) and specificity was 0.59 (CI: 0.51 to 0.67).…”

Section: Discussionmentioning

confidence: 99%

Microalbuminuria is a predictor of adverse pregnancy outcomes including preeclampsia

Jayaballa

Sood

Alahakoon

et al. 2015

Pregnancy Hypertension: An International Journal of Women's Car

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Comparison of pregnancy outcomes in women with hypertensive disorders of pregnancy using 24‐hour urinary protein and urinary microalbumin to creatinine ratio

Abstract: The spot urinary microalbumin to creatinine ratio dipstick is a good screening test to rule out clinically significant proteinuria.

Cited by 19 publications

References 11 publications

Comparison of obstetric outcome in pregnant women with and without microalbuminuria

Comparison of obstetric outcome in pregnant women with and without microalbuminuria

Comparison of pregnancy outcome among nulliparas with and without microalbuminuria at the end of the second trimester

Microalbuminuria is a predictor of adverse pregnancy outcomes including preeclampsia

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