COMPARISON OF PREOPERATIVE RECTAL DICLOFENAC AND RECTAL PARACETAMOL &amp; THEIR COMBINATION FOR POSTOPERATIVE ANALGESIA IN PAEDIATRIC PATIENTS

Patel, Siddharth; Kapdi, Manisha

doi:10.26860/ijabms.2020.22/b.35.8

Cited by 1 publication

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“…The use of rectal route is efficient as it avoids first pass metabolism. This was reflected in the conclusion of the recent study by Patel et al 15 who concluded that compared to rectal diclofenac sodium suppository and rectal paracetamol suppository alone, Rectal Diclofenac-paracetamol combination suppository delivered safe, effective, and cost-efficient analgesia.…”

Section: Discussionmentioning

confidence: 95%

Postoperative Analgesia After Inguinal Herniotomy in Children; A Comparison of Combination of Intravenous Paracetamol and Rectal Diclofenac with Caudal Bupivacaine

Sabih¹,

Zahir

Zulfiqar

et al. 2023

Ann Pak Inst Med Sci

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Objective: To compare the efficacy of intravenous paracetamol and rectal diclofenac combination with caudal block using 1ml/kg of 0.25% bupivacaine in the management of post-operative pain following paediatric inguinal herniotomy. Methodology: This quasi-experimental study was conducted at the Department of Anesthesia, Holy Family Hospital, Rawalpindi, from February 2020 to August 2020. A total of 342 children aged 2-12 years requiring inguinal herniotomy were enrolled after satisfying the inclusion and exclusion criteria. Computer-generated random numbers were used to split the patients into two groups. Group A received intravenous paracetamol (30 mg/kg) and rectal diclofenac (1mg/kg). Group B received a caudal block using 1ml/kg of 0.25% Bupivacaine. Pain was assessed postoperatively in the PACU by modified Objective Pain Scale (OPS) every 15 minutes for the 1st hour and hourly up till 8 hours. Effective analgesia was defined as a modified OPS score of ≤ 3 for upto 8 hours after shifting to PACU. If at any time, the score was >3 and the patient required a rescue analgesic, effective anaglesia was not achieved. Results: Effective analgesia was achieved in 82.46% of the patients (n=141) in Group-A versus 87.13% patients (n=149) in Group-B (p-value: 0.23). Conclusion: There is no significant difference in the efficacy of analgesia in paracetamol/diclofenac combination group compared with caudal bupivacaine group.

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Section: Discussionmentioning

confidence: 95%