Comparison of profile of retinopathy of prematurity in semiurban/rural and urban NICUs in Karnataka, India

Murthy, Krishna R; Murthy, Praveen R; Shah, Dhwani; Nandan, Madhav R; Niranjan, H S; Benakappa, Naveen

doi:10.1136/bjophthalmol-2012-302801

Cited by 42 publications

(46 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…12 The incidence of ROP in this study was 40% which falls within the range of 15.6%-47.3% reported from previous studies in India. 9,[13][14][15][16] ROP is a multifactorial disease with risk factors such as low GA, LBW, sepsis, oxygen therapy, RDS, and blood transfusion shown to influence its incidence. 17 Of these LBW, low GA and oxygen therapy are considered the most important risk factors for ROP with LBW being the greatest predictor of severity.…”

Section: Resultsmentioning

confidence: 99%

Study of retinopathy of prematurity in high risk infants

Parikh

Patel

Hapani

2018

Int J Contemp Pediatr

View full text Add to dashboard Cite

Background: Retinopathy of prematurity is a vaso-proliferative disorder of retina in premature babies. The objective of this study was to study retinopathy of prematurity in premature babies and to study associated risk factors.Methods: Study was a prospective study was conducted among infants in high risk follow up clinic of our department KT Children Hospital, tertiary teaching hospital attached to Government medical college, Rajkot. Sample size of study was conducted on 100 high risk neonates who were brought to high risk follow up clinic at K T children hospital, Rajkot.Results: Out of studied 100 infant, 40% developed ROP, 12% developed stage 1 ROP, 13% developed stage 2 ROP,15% developed stage 3 ROP. Out of 100 cases 40% were ROP positive.15% occurred between 28-30 weeks of gestation. In 31-33 weeks of gestation 82.5%. In 34-36 weeks of gestation 2.5%. 15% of cases between 740-1000 gm of birth weight developed ROP.67.5% between 1000-1500 gm of birth weight developed ROP.15% between 1500-2000 gm of birth weight developed ROP.2.5% between 1500-2000 gm of birth weight developed ROP. 70 newborns received oxygen, 95% of newborns developed ROP. 5% newborns who have not received oxygen developed ROP. In present study there is association of ROP with oxygen therapy. 40 cases had apnea. Out of 40 cases 55% had ROP. Association between apnea and ROP. 21 received blood products.57% of them had ROP. Association between blood transfusion and ROP. 20 received ventilation. 75% of them had ROP. Association between ventilation and ROP. Out of 40 positive newborns there 17 were male and 23 were female. No difference in distribution of ROP in male and female sex. Significant relationship between gestational age, O2 therapy, mechanical ventilation, apnea and blood products. Insignificant relationship between sexes.Conclusions: This study has identified ROP is found to be associated with gestational age, o2 therapy, mechanical ventilation, apnea and blood products.

show abstract

Section: Resultsmentioning

confidence: 99%

Study of retinopathy of prematurity in high risk infants

Parikh

Patel

Hapani

2018

Int J Contemp Pediatr

View full text Add to dashboard Cite

show abstract

“…[24252627] More than one-sixth required active intervention. The parents of the rest were counseled and infants were monitored without intervention.…”

Section: Discussionmentioning

confidence: 99%

“…[25] A study in Karnataka, India, the incidence of ROP in urban population was 16.5%. [26] The incidence of ROP in a pediatric unit of hospital in Pune was 23%. [27] Although the criteria for screening were similar, there was wide variation in the incidence of ROP.…”

Section: Discussionmentioning

confidence: 99%

A mobile team for screening of retinopathy of prematurity in India: Cost - effectiveness, outcomes, and impact assessment

Kelkar¹,

Kelkar²,

Sharma³

et al. 2017

Taiwan J Ophthalmol

View full text Add to dashboard Cite

PURPOSE:To study the cost effectiveness, outcomes and impact of retinopathy of prematurity (ROP) screening and management model for urban neonatal intensive care units (NICUs).STUDY DESIGN:Public health intervention study.METHODS:This study was conducted in 2013. Staff of a mobile unit assessed all infants aged less than 34 weeks of Gestation age at birth and/or birth weight 1700 GM or less admitted in five NICUs between 2013 and 2015. A trained ophthalmologist performed bedside ROP screening through dilated pupils using indirect ophthalmoscope. ROP was graded and managed as per the International Classification of Retinopathy of Prematurity treatment guidelines. Counseling and laser treatment were the interventions. The incidence, grade and determinants of ROP were estimated. Direct and indirect costs were calculated to estimate the unit cost of screening and managing a child with ROP using the model.RESULTS:The study sample included 102 preterm/underweight infants. The prevalence of ROP of different grades in either eye was 32% (95% Confidence Intervals (CI): 23.2–41.5). ROP stage I was present in 75% of these eyes. The model could help in preventing/reducing visual disability in 4 infants with advanced stages of ROP. The unit cost of ROP screening, identifying one child with ROP and addressing visual disability due to ROP was US $ 198.9, 596.7 and 4,137.4 respectively.CONCLUSION:A mobile screening is likely feasible and cost-effective method to detect ROP and offer timely intervention for NICU in urban areas with limited resources.

show abstract

“…Previously published reports studying telemedicine approaches to ROP do not detail the processes involved in certifying non-physician TRs, except one that describes a brief training session for non-expert graders consisting mostly of medical students and ophthalmology residents. 7 Previous studies on ROP telemedicine have used different type of readers: single ROP experienced ophthalmologist as an unmasked reader; 3 single masked ROP experienced ophthalmologists 8,9 ; more than 2 masked ROP experienced ophthalmologists; 8,9 ROP experienced ophthalmologists who performed clinical exams and evaluated retinal images from the same infants after a few months; 12 and non-physician imagers who also read the images they had taken. 13 Previous clinical studies have not studied a system to evaluate the competency of remote non-physician graders.…”

Section: Discussionmentioning

confidence: 99%