Comparison of Propofol and Thiopental in Sedation of Children for MRI Procedure

Abstract

Aım: Children who will be sedated for MRI was compared about the propofol and thiopental application. Materıal and Methods: ASA I-II, 160 cases between 1 month and 8 years old were included. Initial systolicblood pressure (SBP), diastolic blood pressure (SBP), heart rate, oxygen saturation (SPO2) values were recorded. Group I: Propofol 2 mg / kg bolus, Group II: Thiopental sodium 2 mg / kg bolus. The University of Michigan Sedation Scale (UMSS) was used to determine the sedation level. Age, sex, body weight, ASA, MRI region, total amount of drug used were recorded. The technician performing MRI evaluated the quality of the shots with a verbal scoring system ranging from 1 to 3. Results: The total dose given to the males was 43.6 ± 20 mg and the females were 38.3 ± 18 mg. The difference was not statistically significant (p = 0.944). In terms of processing time, the difference was statistically significant (p = 0.09). UMSS averaged 2.81 in Group I and 2.60 in Group II, with a statistically significant difference between groups (p = 0.003). There was a statistically significant difference between groups in terms of side effects, desaturation, prolonged sedation and nausea and vomiting (p <0.05). Conclusıon: Because of the minimal side effects and rapid induction, propofol was under the control of anesthesiologist. Unlike our previous literature, it could be used effectively and reliably even in younger infants.