Comparison of Psychiatric Symptoms in Carcinoma of the Pancreas with Those in Some Other Intra-abdominal Neoplasms

Fras, Ivan; Litin, Edward M.; Pearson, John

doi:10.1176/ajp.123.12.1553

Cited by 184 publications

(80 citation statements)

References 23 publications

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“…Os primeiros estudos investigando depressão associada a câncer de pâncreas indicavam taxas elevadas, ao redor de 33% a 50% 11,12 . Entretanto, em estudo recente, a prevalência de depressão foi 21% em 258 casos de câncer de pâncreas, avaliados retrospectivamente 13 .…”

Section: Câncer De Pâncreasunclassified

Depressão e câncer

Bottino¹,

Fráguas

Gattaz

2009

Rev. psiquiatr. clín.

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ResumoA depressão é o transtorno psiquiátrico mais comum em pacientes com câncer, com prevalências variando de 22% a 29%. Essa variabilidade está associada a sítios do tumor, estágio clínico, dor, funcionamento físico limitado, além da existência de suporte social. A depressão associa-se a um pior prognóstico e aumento da mortalidade pelo câncer. Síndromes depressivas podem ser uma consequência das terapias antineoplásicas, como ocorre em 21% a 58% dos pacientes recebendo interferon-alfa. Sentimentos de tristeza e desespero podem inibir a procura de cuidado pelos pacientes, dificultando o reconhecimento da depressão. O tratamento com antidepressivos é efetivo e melhora a adesão aos tratamentos do câncer, reduzindo efeitos adversos como náusea, dor e fadiga. Em pacientes com câncer, tratamento prévio com antidepressivos pode minimizar sintomas depressivos induzidos por interferon-alfa. O tratamento com antidepressivos parece ser uma estratégia efetiva para prevenir o desenvolvimento da depressão induzida por interferon-alfa. Intervenções psicossociais, como técnicas de relaxamento, terapia individual e em grupo, também podem ser utilizadas na redução dos sintomas depressivos e de estresse em pacientes com câncer. Bottino SMB, et al. / Rev Psiq Clín. 2009;36(3):109-15Palavras-chave: Depressão, câncer, diagnóstico, tratamento. AbstractDepression is the most common psychiatric disorder in patients with cancer, with prevalence rates ranging from 22% to 29%. This variability is associated to cancer sites, clinical stages, pain, limited physical functioning, beyond the existence of social support. Depression is associated to poorer prognosis and higher cancer mortality. Depressive syndromes can be a consequence of the antineoplasic therapies, as occurs in 21% to 58% of the patients treated with alfa-interferon. Sadness and desperation can inhibit the search for care by the patients, and difficult depression recognition. Antidepressant treatment is effective, and improve the adherence to cancer treatments, reducing side effects as nausea, pain and fatigue. In cancer patients, pretreatment with antidepressants seems to minimize depressive symptoms induced by interferon-alfa. Psychosocial interventions as relaxing techniques, group and individual psychotherapies can also be applied to reduce depressive and stress symptoms in patients with cancer.Bottino SMB, et al. / Rev Psiq Clín. 2009;36(3):109-15

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Section: Câncer De Pâncreasunclassified

Depressão e câncer

Bottino¹,

Fráguas

Gattaz

2009

Rev. psiquiatr. clín.

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“…A well-described study of 139 patients who were admitted for possible colon or pancreatic cancer reported that 76% of patients with pancreatic cancer had depressive symptoms prior to surgery compared to 17% of patients with colon cancer. 30 A small National Cancer Institute study also revealed major depressive symptoms in half of the patients with pancreatic cancer compared with none in patients with gastric cancer. 31 A large literature of retrospective reviews has tried to connect the issue of unrelieved pain and misdiagnosis to depressive symptoms in this illness.…”

Section: Depressionmentioning

confidence: 99%

Palliative Care in Pancreatic Cancer

Brescia

2004

Cancer Control

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Background: Pancreatic cancer is a formidable health problem, representing the 10th most common malignancy in the United States and the 4th most common cause of all cancer deaths. The overall 5-year survival rate is 4%, making this disease a model tumor in which topathology and biology of the disease, as well as improved diagnostic imaging and staging studies, the overall 5-year survival rate remains 4% for all stages and races. Adenocarcinoma of the pancreas comprises 90% to 95% of all malignant tumors of the exocrine pancreas. It is one of the most lethal malignancies, and its geographic location within the body makes imaging studies and biopsy procedures more difficult compared with other tumors. There are no clear-cut high-risk populations to follow, even if effective screening procedures were available. More problematic is the reality that presenting symptoms are vague, diverse, and long-evolving before medical attention is sought.The clinical presentation is often dramatic, with "painless" obstructive jaundice. There is often a history of mild but progressive discomfort or pain in the mid-abdomen, occasionally with radiation to the back, and usually noted worse at the end of the day.

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“…Magni in 1986 used a structured psychiatric interview and found that 8% of the 220 geriatric medically ill inpatients suffered from major depression, 22% had dysthymia and 6% had atypical depression. 8 Thus prevalence of major depression increases on comparing community, primary care, inpatients and severely medically ill patients. Several studies have confirmed the prevalence of depression in cancer patients in between 20 and 50%.…”

Section: Hamdmentioning

confidence: 99%

Study of Depression in Women With Cervical and Breast Cancer

Mishra¹,

Dwivedi²

2015

jemds

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BACKGROUND:There is considerable lack of scientific estimate of depressive disorder among cancer patients in India. OBJECTIVES: (1) To associate the depressive disorders between the cervical cancer and breast cancer patients and (2) to compare the level of depression score among cervical and breast cancer patients, and with medically ill inpatient population with some other medical illnesses. SETTING AND DESIGN: A cross-sectional study at inpatient Department of Bharath Cancer Hospital and JSS Medical College Hospital, Mysore. MATERIAL AND METHOD: The study was conducted on admitted thirty breast and thirty cervical cancer inpatients in medical ward of JSS Hospital and Bharath Cancer Hospital, Mysore from December 2007 to august 2009. Data analysis was done for the both groups of cancer and with thirty control group of medically ill inpatient population with some other medical illnesses. Detailed psychological, sociodemographic characteristics were recorded in proforma specially designed for the study. Depression was assessed using MINI plus, HAMD scale and scoring was done. STATISTICAL ANALYSIS: Descriptive statistics, Cross tabs procedure, repeated measure ANOVA statistical methods were carried out through the SPSS for Windows (version 16.0). RESULTS: Major depressive disorder was present in 16.7% of breast cancer and 23.3% of cervical cancer patients.. There was no significant association between type of cancer (Breast cancer and cervical cancer) and depressive disorder. Depression score was found high in cervical cancer cases compare to breast cancer cases though difference in these scores were not statistically significant in between two cancer groups. Depression score was high and significant in both cancer groups as compare to control group. CONCLUSION: Depression is more prevalent in cancer patients than in other several medical illneses and adequate knowledge is required for psychosocial interventions and designing programs aimed at improving the quality of life of cancer patients.

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Comparison of Psychiatric Symptoms in Carcinoma of the Pancreas with Those in Some Other Intra-abdominal Neoplasms

Cited by 184 publications

References 23 publications

Depressão e câncer

Depressão e câncer

Palliative Care in Pancreatic Cancer

Study of Depression in Women With Cervical and Breast Cancer

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