Comparison of Resorbable Poly-L-Lactic Acid-Polyglycolic Acid and Internal Palmaz Stents for the Surgical Correction of Severe Tracheomalacia

Sewall, Gregory K.; Connor, Nadine P.; Warner, Thomas T.; Hartig, Gregory K.

doi:10.1177/000348940311200606

Cited by 29 publications

(14 citation statements)

References 10 publications

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“…In the area of stents that could be inserted to keep the patient alive, the time has come to develop stents that adequately address the QoL issues. Newer materials, a better understanding of airway biomechanics [109] and other approaches, such as bioabsorbable stents [125], will lead to improvements.…”

Section: Clinical Experience and Resultsmentioning

confidence: 99%

Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents

Bolliger¹

2006

Eur Respir J

339

276

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Minimally invasive diagnostic and therapeutic approaches in medicine have been applied for a more selective and tailored approach to reduce patients' morbidity and mortality. The efficacy of interventional pulmonology for palliation of patients with central airways obstruction has been established and its curative potential for intralesional treatment of early cancer has raised great interest in current screening programmes. This is due to the fact that surgical resection and systemic nodal dissection as the gold standard is relatively morbid and risky, especially when dealing with individuals with limited functional reserves due to smoking-related comorbidities, such as chronic obstructive pulmonary disease. Furthermore, such comorbidities have been proven to harbour early stage lesions of several millimetres in size without involvement of nodal disease that may be amenable to local bronchoscopic treatment.Therefore, the success of minimally invasive strategies for palliation and treatment with curative intent strongly depends on the diligent identification of the various factors in lung cancer management, including full comprehension of the limits and potential of each particular technique. Maximal preservation of quality of life is a prerequisite in successfully dealing with individuals at risk of harbouring asymptomatic early lung cancer, to prevent aggressive surgical diagnostic and therapeutic strategies since overdiagnosis remains an issue that is heavily debated.In the palliative setting of alleviating central airway obstruction, laser resection, electrocautery, argon plasma coagulation and stenting are techniques that can provide immediate relief, in contrast to cryotherapy, brachytherapy and photodynamic therapy with delayed effects. With curative intent, intraluminal techniques that easily coagulate early stage cancer lesions will increase the implementation of interventional pulmonology for benign and relatively benign diseases, as well as early cancer lesions and its precursors at their earliest stage of disease.

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Section: Clinical Experience and Resultsmentioning

confidence: 99%

Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents

Bolliger¹

2006

Eur Respir J

339

276

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“…Other studies showed that large bone defects could be repaired using rhBMP-2 on a PLPG sponge (Marukawa et al, 2001). Due to its favorable structure, absorbable PLPG sponges have been used in an animal model for tracheomalacia (Nalwa et al, 2001;Sewall et al, 2003).…”

Section: Discussionmentioning

confidence: 99%

Influence of rhBMP-2 on bone formation and osseointegration in different implant systems after sinus-floor elevation. An in vivo study on sheep

Gutwald

Haberstroh

Stricker

et al. 2010

Journal of Cranio-Maxillofacial Surgery

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SUMMARY.Background: Several studies have reported certain bone morphogenic proteins (BMPs) to have positive effects on bone generation. Although some investigators have studied the effects of human recombinant BMP (rhBMP-2) in sinus augmentation in sheep, none of these studies looked at the placement of implants at the time of sinus augmentation. Furthermore, no literature could be found to report on the impact that different implant systems, as well as the positioning of the implants had on bone formation if rhBMP-2 was utilized in sinus-lift procedures. Purpose: The aim of this study was to compare sinus augmentation with rhBMP-2 on a poly-D, L-lactic-co-glycolic acid gelatine (PLPG) sponge with sinus augmentation with autologous pelvic cancellous bone in the maxillary sinus during the placement of different dental implants. Materials and methods: Nine adult female sheep were submitted to bilateral sinus-floor elevation. In one side (test group) the sinus lift was performed with rhBMP-2 on a PLPG-sponge, while the contralateral side served as the control by using cancellous bone from the iliac crest. Three different implants (Bränemark Ò , 3i Ò and Straumann Ò ) were inserted either simultaneously with the sinus augmentation or as a two staged procedure 6 weeks later. The animals were sacrificed at 6 and 12 weeks for histological and histomorphometrical evaluations during which boneto-implant contact (BIC) and bone density (BD) were evaluated. Results: BD and BIC were significantly higher at 12 weeks in the test group if the implants were placed at the time of the sinus lift (p \ 0.05). No difference was observed between the different implant systems or positions. Conclusions: The use of rhBMP-2 with PLPG-sponge increased BIC as well as BD in the augmented sinuses if compared to autologous bone. Different implant systems and positions of the implants had no effect on BIC or BD. Ó 2010 European Association for Cranio-Maxillo-Facial Surgery

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“…Similar devices have been reported for other clinical uses and would potentially decrease or negate the need for reinterventions to remove the stent [40,41]. In a single case report, an esophageal stent constructed of polyglycolide, the same material found in absorbable sutures and with a biological life of 3-6 months, was used to palliate a malignant esophageal stricture [42].…”

Section: Future Directionsmentioning

confidence: 90%

Retrievable Esophageal Stents for Benign Indications

et al. 2007

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Until recently, esophageal stents have not been a realistic option for the management of benign disease owing to difficulty removing the stents and associated high complication rates. However, progress in esophageal stent design has led to the development of retrievable esophageal stents. Clinical experience has shown promise for the management of benign esophageal diseases with retrievable stents, including refractory strictures, esophageal leaks, fistula and perforations. They have been shown to be safe and effective, though stent migration remains a concern. This article reviews the current designs, indications, efficacy and complications of retrievable esophageal stents.

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Comparison of Resorbable Poly-L-Lactic Acid-Polyglycolic Acid and Internal Palmaz Stents for the Surgical Correction of Severe Tracheomalacia

Cited by 29 publications

References 10 publications

Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents

Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents

Influence of rhBMP-2 on bone formation and osseointegration in different implant systems after sinus-floor elevation. An in vivo study on sheep

Retrievable Esophageal Stents for Benign Indications

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