2022
DOI: 10.1371/journal.pone.0273789
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Comparison of rheumatoid arthritis composite disease activity indices and residual activity in a Brazilian multicenter study- REAL study

Abstract: Introduction Rheumatoid arthritis (RA) composite disease activity indices have become handy tools in daily clinical practice and crucial in defining remission or low disease activity, the main target of the RA treatment. However, there is no definition of the best index to assess disease activity in clinical practice. Objectives To compare the residual activity among the indices with the ACR/EULAR remission criteria (Boolean method) to identify the most feasible for assessing remission in daily practice, als… Show more

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“…Rheumatologists now routinely employ composite measurements to determine the severity of RA. The DAS28-ESR has been validated for measuring therapeutic response and is employed in most clinical trials and daily practice (39) . The reliability and validity of this instrument in clinical studies have been thoroughly established.…”
Section: Discussionmentioning
confidence: 99%
“…Rheumatologists now routinely employ composite measurements to determine the severity of RA. The DAS28-ESR has been validated for measuring therapeutic response and is employed in most clinical trials and daily practice (39) . The reliability and validity of this instrument in clinical studies have been thoroughly established.…”
Section: Discussionmentioning
confidence: 99%