Comparison of SEER Sonorheometry With Rotational Thromboelastometry and Laboratory Parameters in Cardiac Surgery

Abstract

SEER sonorheometry demonstrates significant correlation with ROTEM for determining Clot Stiffness and assessing Fibrinogen Contribution. SEER sonorheometry results can provide valuable information about the coagulation status in patients undergoing cardiac surgery using CPB.

Clinical utility of the Quantra® point‐of‐care haemostasis analyser during urgent cardiac surgery

“…We have shown that point-of-care testing using the novel Quantra system provides useful data for guiding transfusion management and have provided reference values corresponding to laboratory triggers for transfusion. In particular, our study suggests that the Quantra demonstrates high negative predictive value for coagulation abnormalities detected by laboratory tests (low platelets, prolonged PT/ aPTT); these results mirror those reported in previous studies [7][8][9] and suggest that the Quantra may be useful for identifying patients where blood component transfusion is not indicated. It also suggests that the Quantra is more useful than thromboelastography and may make the laboratory platelet count redundant for predicting the need for platelet transfusion.…”

“…Viscoelastic testing devices can be used before, during and after bypass to assess the coagulation system, but not all parameters during the three time‐points are equally valid at predicting bleeding and guiding the use of blood products . We only tested blood taken from the arterial cannula, as recommended by Groves et al.…”

“…Coagulopathic bleeding during cardiac surgery, especially in patients undergoing urgent or emergency procedures, is associated with increased blood component transfusion and prolonged hospital stay, which results in higher healthcare costs and a poorer outcome for patients [14,15]. We studied patients undergoing urgent surgery for unstable cardiac disease, who were nearly all taking antiplatelet medication; 68% of patients were transfused Viscoelastic testing devices can be used before, during and after bypass to assess the coagulation system, but not all parameters during the three time-points are equally valid at predicting bleeding and guiding the use of blood products [2,7,9]. We only tested blood taken from the arterial cannula, as recommended by Groves et al [18].…”

“… Our aim was to compare the effect on blood component transfusion of the novel ultrasound technique used in the Quantra point‐of‐care device with laboratory and TEG testing, in patients undergoing urgent cardiac surgery and therefore at higher risk for blood transfusion. Previous studies in cardiac surgery have focused on elective patients at low risk of transfusion or spinal surgery . This study was designed to establish baseline ranges for Quantra QPlus parameters after higher risk cardiac surgery and to provide a first indication of transfusion thresholds for Quantra QPlus parameters for validation in future studies .…”

“…However, whole blood point-of-care testing using viscoelastic testing devices is thought to reflect true haemostasis more closely and may, therefore, be better [3,4]. [7][8][9]. This study was designed to establish baseline ranges for Quantra QPlus parameters after higher risk cardiac surgery and to provide a first indication of transfusion thresholds for Quantra QPlus parameters for validation in future studies [10].…”