A field experiment was conducted for determination of crop coefficient (KC) and water stress coefficient (Ks) for wheat crop under different salinity levels, during 2015-2016. Complete randomized block design of five treatments were considered, i.e., 0.51 dS·m -1 (fresh water, FW) as a control treatment and other four saline water treatments (4, 6, 8 and 10 dS·m -1 ), for S 1 , S 2 , S 3 and S 4 with three replications. The results revealed that the water consumed by plants during the different crop growth stages follows the order of FW > S 1 > S 2 > S 3 > S 4 salinity levels. According to the obtained results, the calculated values of KC significantly differed from values released by FAO paper No 56 for the crops. The Ks values clearly differ from one stage to another because the salt accumulation in the root zone causes to reduction of total soil water potential (Ψ t ), therefore, the average values of water stress coefficient (Ks) follows this order; FW(1.0) = S 1 (1.0) > S 2 (1.0) > S 3 (0.93) > S 4 (0.82). Precise data of crop coefficient, which is required for regional scale irrigation management is lacking in developing countries. Thus, the estimated values of crop coefficient under different variables are essential to achieve the best management practice (BMP) in agriculture.