Aims and Objectives: The success of composite resin depends mainly on the bond strength of the restoration to the tooth structure. The type of adhesive, the substrate and the surface treatment are the most important factors that affect the bond strength of composite resin restorations. Despite the fact that phosphoric acid is the standard in enamel pretreatment with the best shear bond strength shown with composites in primary teeth. The aprismatic outer enamel layer distinctive to primary teeth could compromise the bond strength and result in a defective superficial etching pattern. Lasers have been studied as surface pretreatment agents with limited applications in primary teeth. Primary enamel pre-conditioning using erbium, chromium:yttrium-scandium-gallium-garnet (Er, Cr:YSGG) yielded controversial results as regards to enhancing enamel bond strength of composite resins to primary enamel. Aim: The aim of the study is to evaluate and compare the shear bond strength of composite resin bonded to enamel which is pretreated using conventional phosphoric acid etchant and Er,Cr:YSGG laser pretreatment. Materials and Methods: Thirty extracted human primary molar teeth were divided into three groups, (N=10) in each (Groups I, II and III). Group I, prepared surface of enamel was etched using 37% phosphoric acid (Scotchbond, 3M). Group II, enamel was surface treated by an Er, Cr: YSGG laser system (Waterlase MD, Biolase Technology Inc., San Clemente, CA, USA) and Group III, a combination of etching and laser treatment was performed. The bonding agent (Scotchbond Multipurpose, 3M) was then applied over the test areas and light cured. Composite resin (Filtek ™ Z250 XT Nano-hybrid Universal restorative, 3M Espe) was later applied and light cured. The samples were finally tested for the shear bond strength. Results: The Mean shear bond strength for Group III was the highest (23.2 ± 0.44MPa) Followed by Group I (17.4 ± 0.66MPa), these values were significantly higher (P < 0.01) than that of Group II (10.1 ± 0.71MPa).