Comparison of short term results of single injection of autologous blood and steroid injection in tennis elbow: a prospective study

Abstract

BackgroundIt has been recently reported that local injection of autologous blood in tennis elbow offers a significant benefit by virtue of various growth factors contained therein. The objective of our study was assessment of efficacy of autologous blood injection versus local corticosteroid injection in the treatment of tennis elbow.Methods and trial designA single blinded, prospective parallel group trial was undertaken. 50 consecutive patients of untreated lateral epicondylitis were enrolled. Randomisation was done on alternate basis and two groups were constituted, first one receiving steroid injection and second one injection of autologous blood. Both groups were evaluated at 2 and 6 weeks for pain relief and stage of disease.ResultsBaseline evaluation showed no difference between the two groups (chi square test, P > 0.05). Between group analysis at 2 weeks showed no difference in pain relief and Nirschl stage (unpaired t test, P > 0.05). Evaluation at 6 weeks demonstrated a significant decrease in pain levels and stage of disease in blood group (unpaired t test, p < 0.05).ConclusionsAutologous blood injection was more effective than steroid injection in the short term follow up in tennis elbow.

Injection of Autologous Blood versus Corticosteroid for Lateral Epicondylitis: A Randomised Controlled Study

“…20,21 In a review of 12 studies for treatment of lateral epicondylitis, the use of autologous blood, corticosteroid, platelet-rich plasma, placebo, or extracorporeal shock wave therapy were compared (Table 3). 6,13,14,[22][23][24][25][26][27][28][29][30] Autologous blood injection was more effective in the long term than corticosteroid injection in improving pain and tenderness, although corticosteroid injection enabled faster pain relief. Extracorporeal shock wave therapy was also more effective than corticosteroid injection in the long term.…”

Efficacy and Safety of Autologous Blood Products Compared With Corticosteroid Injections in the Treatment of Lateral Epicondylitis: A Meta‐Analysis of Randomized Controlled Trials

“…In 6 trials [26‐28,30,32,33], subjects were treated with AB, and in 4 trials [15,29,31,34], subjects were treated with PRP in the experimental group. Therapies in the control group varied among the different studies; in 5 studies, control subjects were treated with methylprednisolone [26,27,32‐34], in 2 studies they were treated with Kenacort (triamcinolone) [15,31], and in 3 studies they were treated with an undefined corticosteroid [28‐30]. A combination with local anesthetics, such as lidocaine or prilocaine, was applied in 8 trials, whereas the remaining 2 studies [29,34] made no mention of such a combination.…”

“…Blinding of subjects, treating doctors, and outcome assessors were judged as LRB in 3 trials [15,28,31], 2 trials [28,33], and 5 trials [15,26,28,31,32], respectively. ITT analysis was found as LRB in 6 trials [14,15,26,30,32,33]. Four trials [15,26,29,31] provided detailed registration information without selective reporting of pre‐established outcomes.…”

The Comparison of ESWT, Physiotherapy and Local Steroid Injection Methods in The Treatment of Lateral Epicondylitis

“…Lateral epikondilit tedavisinde birçok yöntem kullanılmaktadır. Sadece bekle-gör, [2] steroid olmayan antienflamatuvar ilaç (SOAEİ), [3] breys, [4] egzersiz, [5][6][7][8] cyriax fizyoterapi (Mill manevrası ile birlikte yapı-lan derin transvers friksiyon masajı), [8] akupunktur, [9] proloterapi, [10] botulinum toksin enjeksiyonu, [11] otolog kan enjeksiyonu, [12] fizyoterapi (FT) , [2,13] lokal steroid enjeksiyonu, [2,3,[12][13][14] ekstrakorporeal şok dalga tedavisi (ESWT) [13][14][15][16] ve tenotomi [15] en yaygın kullanılan tedavi yöntemleridir. Bazı yazarlar ESWT'nin lateral epikondilit tedavisinde etkili olmadığını belirtirken [17] bazı-ları da lokal steroid enjeksiyonunun ESWT'den daha etkili olduğunu belirtmiştir.…”