Comparison of single-session transarterial chemoembolization combined with microwave ablation or radiofrequency ablation in the treatment of hepatocellular carcinoma: a randomized-controlled study

Abstract

Combined ablation with chemoembolization is superior in the treatment of nonresectable single masses larger than 4 cm. Transcatheter arterial chemoembolization and ablation can be performed safely and successfully during a single session, which has not been found to decrease the response rates to treatment. Combined treatment with MWA is more effective in terms of tumor response, and results in the same complication rate as with radiofrequency, but less than chemoembolization alone.

Combined transarterial chemoembolization and microwave ablation versus transarterial chemoembolization in BCLC stage B hepatocellular carcinoma

“…The improvement is mainly attributed to the reduction of heat-sink effect due to the vascular outflow of the liver (17). Furthermore, a randomized-controlled study in 2016 found that TACE-MWA combination therapy was more effective than TACE-RFA combination therapy in unresectable single-lesion HCC patients (18).…”

Hepatocellular Carcinoma (HCC) in Egypt: A comprehensive overview

“…Figure 1 represents different options for HCC therapeutic modalities used. Recently, results of studies for HCC treatment and prevention of complication have been reported [86][87][88][89]. Details about clinical trials in Egypt will be discussed in HCC research section.…”

Comparison of microwave ablation and radiofrequency ablation for hepatocellular carcinoma: a systematic review and meta-analysis

“…After a preliminary review, 418 papers were excluded because they were considered irrelevant studies, case reports, animal studies, comment letters, or reviews. Among 32 potentially relevant papers, we excluded five studies in which patients were treated with embolization combined with MWA or RFA [12][13][14][15][16] and another seven because of insufficient data [17][18][19][20][21][22][23]. Six studies were excluded because of duplicate data [24][25][26][27][28][29].…”