Comparison of some hematological parameters between male and female patients infected with COVID-19

Abed, Hayder H.; Al-Ziaydi, Ahmed Ghdhban; Taher, Ihab Abbas; Dulaimi, Ahmed K Al

doi:10.3233/hab-220006

Cited by 5 publications

(2 citation statements)

References 29 publications

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“…Despite the unchanged MO count, monocyte distribution width (MDW) was shown to increase in the patients and suggested to be a diagnostic tool in COVID-19 [26]. Leucopenia was also shown to develop in some COVID-19 patients and suggested that WBC count may provide some information about the severity of the cases [27]. Absence of comparison between healthy and COVID-19 infected patients is the limitations of the study.…”

Section: Discussionmentioning

confidence: 85%

Differences in some hematological parameters in adult male and female COVID-19 patients: A retrospective study

Sarihan

2023

Med-Science

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COVID-19 is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2). Depending on the severity of the disease, fever, cough, shortness of breath, more severe pneumonia and death may occur. The aim of this study is to compare some blood parameters between adult male and female patients with COVID-19 to understand the effect of gender on disease pathogenesis. For this purpose, the levels of blood serum the D-dimer, white blood cells, monocyte, lymphocyte, platelet, glucose, hemoglobin and Prothrombin Time/INR were measured in a total of 3101 COVID-19 patients whose 1649 were males and 1452 were females. Statistically significant differences were observed in platelet, white blood cells, Prothrombin Time/INR, hemoglobin and monocyte levels while no differences were detected in lymphocyte, D-dimer, and blood glucose levels between male and female patients. The results indicate that platelet, white blood cells, Prothrombin Time/INR, hemoglobin and monocyte levels were significantly higher in males as compared to female patients with COVID-19.

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Section: Discussionmentioning

confidence: 85%

Differences in some hematological parameters in adult male and female COVID-19 patients: A retrospective study

Sarihan

2023

Med-Science

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“…Venous blood samples of up to 5 ml were taken from the vein by using a 5 ml syringe. The samples were kept for 30 minutes at room temperature and then the tubes were transported to centrifugation at 1800 rpm for twenty minutes at room temperature [15]. Serum was kept in separate tubes under frozen conditions until the samples were used for albumin and C-reactive protein tests.…”

Section: Specimen Collectionmentioning

confidence: 99%

Study of Albumin, C-Reactive Protein and Calprotectin as Non-Invasive Indicators for the Diagnosis and Differentiation of Inflammatory Bowel Disease

Ali,

Abed,

Nayif

et al. 2024

SJLSA

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Background. Inflammatory bowel disease (IBD) is defined as an “inflammatory conditions of the colon and small intestine”. The main forms of IBD are ulcerative colitis and Crohn’s disease. The study aims to evaluate fecal calprotectin with albumin and C-reactive protein as non-invasive indicators of (IBD), mainly in patients with digestive symptoms, who are offered for endoscopic-assessment. Methods. The study includes 104 participants, who are divided into the control, Crohn’s disease, and ulcerative colitis groups. Gender, age, BMI, albumin, C-reactive protein (CRP), as well as fecal calprotectin are measured. Results. The results show a significant increase in C-reactive protein and calprotectin (26.77 ± 1.485 mg/l and 419.8 ± 16.99 µg/mg, respectively) in patients with ulcerative colitis, compared to the control group, which shows a mean value of 6.567 ± 1.802 mg/l and 92.98 ± 10.94 µg/mg for C-reactive protein and fecal calprotectin, respectively. The highest value of the CRP result in patients with Crohn’s disease is 40.82 ± 2.191 mg/l and the highest significant difference in calprotectin value is 296.2 ± 17.87 µg/mg, related to the control. Conclusion. The results show high and significant differences in serum C-reactive protein and fecal calprotectin in the patients with ulcerative colitis and Crohn’s disease compared to the healthy people in the control group. In addition, the results show a significant difference in serum C-reactive protein and fecal calprotectin between the ulcerative colitis and Crohn’s disease groups. The results of the study suggest the use of these tests as non-invasive indicators to assess the diagnosis and its differentiation.

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Integration of nanobiosensors into organ-on-chip systems for monitoring viral infections

Zhang,

Kim,

Lee

et al. 2024

Nano Convergence

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The integration of nanobiosensors into organ-on-chip (OoC) models offers a promising advancement in the study of viral infections and therapeutic development. Conventional research methods for studying viral infection, such as two-dimensional cell cultures and animal models, face challenges in replicating the complex and dynamic nature of human tissues. In contrast, OoC systems provide more accurate, physiologically relevant models for investigating viral infections, disease mechanisms, and host responses. Nanobiosensors, with their miniaturized designs and enhanced sensitivity, enable real-time, continuous, in situ monitoring of key biomarkers, such as cytokines and proteins within these systems. This review highlights the need for integrating nanobiosensors into OoC systems to advance virological research and improve therapeutic outcomes. Although there is extensive literature on biosensors for viral infection detection and OoC models for replicating infections, real integration of biosensors into OoCs for continuous monitoring remains unachieved. We discuss the advantages of nanobiosensor integration for real-time tracking of critical biomarkers within OoC models, key biosensor technologies, and current OoC systems relevant to viral infection studies. Additionally, we address the main technical challenges and propose solutions for successful integration. This review aims to guide the development of biosensor-integrated OoCs, paving the way for precise diagnostics and personalized treatments in virological research. Graphical Abstract

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Comparison of some hematological parameters between male and female patients infected with COVID-19

Cited by 5 publications

References 29 publications

Differences in some hematological parameters in adult male and female COVID-19 patients: A retrospective study

Differences in some hematological parameters in adult male and female COVID-19 patients: A retrospective study

Study of Albumin, C-Reactive Protein and Calprotectin as Non-Invasive Indicators for the Diagnosis and Differentiation of Inflammatory Bowel Disease

Integration of nanobiosensors into organ-on-chip systems for monitoring viral infections

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