Comparison of Subcutaneous and Intravenous Rehydration in Geriatric Patients: A Randomized Trial

Slesak, Günther; Schnürle, Joachim W.; Kinzel, Eduard; Jakob, Johann; Dietz, Klaus

doi:10.1046/j.1532-5415.2003.51052.x

Cited by 84 publications

(121 citation statements)

References 17 publications

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“…hydration [221,222]. The infused electrolyte solutions should be isotonic, it is recommended that the infused volume should not exceed 3000 mL per day (max.1.500 mL per infusion site), however in the majority of the reported cases, the infused daily volumes do not exceed 1000 mL [218,220,222,223]. The s.c. application is not suitable for patients needing larger volumes, hypertonic or electrolyte-free solutions.…”

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confidence: 99%

“…The infusion of fluids into the subcutaneous tissue e hypodermoclysis e is an easy, effective and safe hydration technique in mild to moderate dehydration, particularly in cognitively impaired patients [219,220,222,223]. There is little discomfort inserting and maintaining the s.c. infusion, and patients are less likely to interfere with s.c. infusions than with i.v.…”

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ESPEN guidelines on nutrition in dementia

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ESPEN guidelines on nutrition in dementia

et al. 2015

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“…Hypodermoclysis is a safe technique for rehydration in mildly dehydrated veterinary patients and mostly used in geriatric patients (Slesak et al, 2003) but balanced electrolyte composition (200-400 mOsm/kg) of solution should be monitored. About 50-200 ml volumes per site can be injected safely (Schaer, 1989;Crowley et al, 1990).…”

Section: Discussionmentioning

confidence: 99%

Iatrogenic Water Intoxication in A Persian Cat: A Case Report

Lodhi¹

2018

ijmvr

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Iatrogenic water intoxication is an uncommon emergency syndrome characterized by acute hyponatremia clinically evident by neurological signs such including nausea, vomiting, seizures, altered mentation and eventually death if not addressed. Patient's serum sodium level is keen regulatory measure for evaluating and treating acute and chronic cases of water intoxication. Present study demonstrates a cat patient in which subcutaneous administration of 5% dextrose in water to compensate body fluid deficits further detoriate the illness and induced neurological signs. Cat was treated with on-hand 0.9% NaCl solution to equilibrate sodium at an appropriate level in intracellular and extracellular spaces. The selection of fluid as supplemental therapy is very critical keeping in view the condition of patient, as it can exaggerate ailment by interrupting vital functions rather than rehabilitating from illness.

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“…(1)(2)(3) However, this technique fell out of favor by 1950, due to reports of fluid overload and circulatory shock occurring after SC infusion of large volumes of solutions without electrolytes, (2,4,5) and the disclosure and notification of disastrous results occurring after infusions provided outside the SC tissue also reached the muscle tissue. Another factor that contributed to the disuse of this technique was the ease of application of intravenous (IV) infusions (5).…”

Section: Introductionmentioning

confidence: 99%

Administração de antibióticos por via subcutânea: uma revisão integrativa da literatura

2012

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Objective: To characterize scientific articles related to the use of antibiotics by the subcutaneous route in patients with difficult venous access in palliative care, regarding local tolerance and therapeutic efficacy. Methods: Integrative literature review conducted in the databases of LILACS, CINAHL, PubMED, EMBASE and the Cochrane Library, using Evidence-Based Practice as a theoretical framework. Results: Seventeen articles were selected with ten different antibiotics, with ceftriaxone being the most studied antibiotic. Therapeutic efficacy was observed based on pharmacokinetic and clinical parameters. The local tolerance was associated with greater dilution of antibiotics. With administration of aminoglycosides, serious injuries and tissue necrosis were observed. A low tolerance reinforced the restriction of use only to this class of antibiotics. Conclusion: The predictions of therapeutic efficacy and good tolerance suggest a possibility to be considered when there is need of an alternative parenteral route of administration, but caution is advised, since none of the studies evaluated patients in palliative care. Keywords: Anti-bacterial agents/administration & dosage; Injections, subcutaneous; Treatment outcome; Palliative care RESUMO Objetivo: Caracterizar os artigos científicos relacionados ao uso de antibióticos por via subcutânea em pacientes com difícil acesso venoso em cuidados paliativos quanto à tolerância local e eficácia terapêutica. Métodos: Revisão integrativa da literatura realizada nas bases de dados LILACS, CINAHL, PUBMED, EMBASE e Biblioteca Cochrane, utilizando-se como referencial teórico a Prática Baseada em Evidências. Resultados: 17 artigos foram selecionados com dez antibióticos diferentes, sendo o Ceftriaxona, o antibiótico mais estudado. Constatou-se a eficácia terapêutica com base nos parâmetros farmacocinéticos e clínicos. A tolerância local esteve associada à maior diluição dos antibióticos. Com administração de aminoglicosídeos, observaram-se lesões graves e necrose tecidual. A baixa tolerância reforça a restrição de uso apenas para essa classe de antibióticos. Conclusão: As previsões de eficácia terapêutica e a boa tolerância sugerem uma possibilidade a ser considerada quando se deseja uma via de administração parenteral alternativa, porém recomenda-se cautela, visto que nenhum dos estudos avaliou pacientes em cuidados paliativos. Descritores: Antibacterianos/administração & dosagem; Injeções subcutâneas; Resultado de tratamento; Cuidados paliativos RESUMEN Objetivo: Caracterizar los artículos científicos relacionados al uso de antibióticos por vía subcutánea en pacientes con difícil acceso venoso en cuidados paliativos en cuanto a la tolerancia local y eficacia terapéutica. Métodos: Revisión integrativa de la literatura realizada en las bases de datos LILACS, CINAHL, PUBMED, EMBASE y Biblioteca Cochrane, utilizándose como referencial teórico la Práctica Basada en Evidencias. Resultados: Fueron seleccionados 17 artículos con diez antibióticos diferentes, siendo la Ceftri...

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Comparison of Subcutaneous and Intravenous Rehydration in Geriatric Patients: A Randomized Trial

Cited by 84 publications

References 17 publications

ESPEN guidelines on nutrition in dementia

ESPEN guidelines on nutrition in dementia

Iatrogenic Water Intoxication in A Persian Cat: A Case Report

Administração de antibióticos por via subcutânea: uma revisão integrativa da literatura

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