Comparison of Tensile Strength of Cyanoacrylate Tissue Adhesive Closure of Lacerations Versus Suture Closure

Bresnahan, Kevin A; Howell, John M.; Wizorek, Joseph J.

doi:10.1016/s0196-0644(95)70007-2

Cited by 40 publications

(20 citation statements)

References 7 publications

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“…21 On the other hand, cyanoacrylate alone for wound closure has exhibited significantly less tensile strength than closure with traditional suture methods. 22 This is in agreement with our clinical observations.…”

Section: Discussionsupporting

confidence: 93%

Late Follow-Up of Cyanoacrylate Usage in Cardiothoracic Surgery

Demirtaş

Çimen

Ketencі

et al. 1999

Asian Cardiovasc Thorac Ann

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In cardiovascular and thoracic surgery, troublesome bleeding and sternal dehiscence can be life-threatening if not managed appropriately. We used commercially available cyanoacrylate adhesive 21 times in 20 sporadic patients for the management of 6 different problems: sternal gluing in 7 cases; anastomotic line reinforcement and bleeding control with a glued Teflon or pericardial patch in 6; right ventricular or superior vena caval patch repair in 5; and 1 case each of left ventricular apical glued Teflon felt, arterial wall reinforcement, and control of air leakage after lung surgery. The mean age of the patients was 55.7 ± 12.5 years, ranging from 34 to 71 years. Successful results were obtained in 18 patients and 17 were alive on follow-up at 7.7 ± 5.5 months (range, 2 to 16 months). We used two different commercial brands of adhesive but obtained good results with only one of these preparations. Although commercially available cyanoacrylate is a new adjunct to cardiac surgery with documented safety and lifesaving results at negligible cost, the appropriate polymer for best results needs to be defined.

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Section: Discussionsupporting

confidence: 93%

Late Follow-Up of Cyanoacrylate Usage in Cardiothoracic Surgery

Demirtaş

Çimen

Ketencі

et al. 1999

Asian Cardiovasc Thorac Ann

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“…[1][2][3][4][5] Average cost per wound closure was very high with staples v/s sutures, 2,6 tensile strength 7 and fibroblastic proliferation and collagination observed higher with sutures v/s staples.…”

Section: Resultsmentioning

confidence: 99%

Incised surgical wound closure with sutures and staples: a controlled experimental study

Kochar

Singh

2015

Int Surg J

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Background: Development of newer techniques of surgical wound closure which are not associated with contamination. Aim is to evaluate advantages and disadvantages of skin closure with sutures and staples. Methods: A controlled experimental study was conducted on guinea pigs divided into two groups of 10 each in NIMS Medical College, Jaipur, in the year 2013. On 5 th POD signs of inflammation (redness, oedema), discharge (serous/seropurulent/purulent), dehiscence (partial or complete) was assessed. On 15 th POD sutures and staples were removed and a strip of scar tissue excised for measurement of tensile strength and histopathology of each wound. Results: Average time taken to close a wound in group 'A' 92.8 sec and in group 'B' 30.3 sec, in group 'A' two showed redness, one swelling & one serous discharge, in group 'B' one redness, two swelling and one serous discharge, tensile strength in group 'A' was 429.9 grams and in group 'B' 393.6 grams., average cost per wound closure was negligible in group 'A' whereas in group 'B' it was Rs. 160/-. There is paucity of literature correlating tensile strength of the healed wound in relation to histopathology of scar tissue. The results were very encouraging, that in group 'A' fibroblastic proliferation and collagination was +++, in group 'B' it was ++ & + respectively. Conclusions: Wound closure with staples is almost three times faster thus time saving but less tensile strength of scar tissue than with sutures. Kochar MP et al. Int Surg J. 2015 Aug;2(3):369-372 International Surgery Journal | July-September 2015 | Vol 2 | Issue 3 Page 370 A single longitudinal skin incision deep till deep fascia was created. Each wound was closed with plain interrupted silk sutures in group 'A' and with staples in group 'B' after achieving haemostasis. All wounds were closed by a single operator to get uniform results. Time taken for skin approximation was measured by an independent observer, wounds after cleaning with povidone-iodine lotion dry gauge dressing applied and covered with adhesive plaster to avoid damage to dressing by self or by other animals. Animals were kept in group of five in different cages. On 5 th POD signs of inflammation (redness, oedema), discharge (serous, seropurulent, purulent), dehiscence (partial, complete) was assessed. Keywords On 15th POD again after anaesthetising the guinea pigs sutures and staples removed, wound length measured and a strip of scar tissue excised from each wound and tensile strength measured by tensilometer. Wound thus created was again closed, dressed and guinea pigs returned to their cages. A block of scar tissue send for histopathology to see -fibroblast with their maturity stages, fibrocytes and their intermediate stages, neovascularisation, collagination, inflammatory cell type and quantity, inflammatory oedema, epithelialisation, gram's staining for bacterias etc.Kochar MP et al. Int Surg J. 2015 Aug;2(3):369-372 International Surgery Journal | July-September 2015 | Vol 2 | Issue 3 Page 371 DISCUSSIONGuinea p...

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“…O butil-cianoacrilato 32 e o octil-cianoacrilato, 33 se comparados ao fio de sutura 5-0, apresentaram uma resistência à tensão, semelhante ao fio de sutura. Os cianoacrilatos somente são eficazes em feridas profundas, até que estes estejam associados a suturas subcutâneas, 34 embora, quando há uma ferida, em regiões de baixa tensão, os adesivos de cianoacrilato são os materiais de escolha para este tipo de síntese.…”

Section: Discussionunclassified

Adesivos à base de cianoacrilato para síntese de tecido mole

Saska

Gaspar

Hochuli‐Vieira

2009

An. Bras. Dermatol.

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Resumo: FUNDAMENTOS -Adesivos teciduais têm sido muito usados para síntese de ferida, em função de ser um método indolor, rápido e de fácil execução. OBJETIVOS -Analisar e comparar compatibilidade dos adesivos, etil-cianoacrilato (Super Bonder) e butilcianoacrilato (Histoacryl), e a reparação de incisões em dorso de ratos entre o fio de sutura e os respectivos adesivos. MÉTODOS -Foram usados 15 ratos. Realizaram-se duas lojas cirúrgicas no dorso. Em cada uma, foi implantado um tubo de polietileno (10mm x 1mm), os quais foram preenchidos com os adesivos Super Bonder (lado direito) e Histoacryl (lado esquerdo). As incisões, do lado esquerdo, foram coaptadas com Super Bonder, e as do lado direito, com Histoacryl. Uma incisão mediana, entre as duas incisões, foi realizada e suturada com fio de seda. Os animais foram mortos, depois de 7(sete), 35(trinta) e 120 (cento e vinte dia) dias. RESULTADOS: Os adesivos usados, no presente estudo, não promoveram reação inflamatória, quando usados para síntese das incisões. Porém, estes adesivos, quando implantados no subcutâneo, promoveram reação inflamatória até 120 (cento e vinte dia) dias, no entanto, a reação é mais intensa com Histoacryl. CONCLUSÕES: Super Bonder e Histoacryl permitem o processo cicatricial dos tecidos incisados; facilitam a sutura das incisões. Desta forma, estes podem ser utilizados para sínteses de feridas, lacerações ou incisões cutâneas. Palavras-chave: Adesivos teciduais; Cianoacrilatos; Hemostáticos; Técnicas de sutura; Teste de materiais; Ratos Abstract: BACKGROUND: Tissue adhesives have been used for the synthesis of wound due to their painless application and quick and easy handling. OBJECTIVES: The purpose of this study was to analyze and compare the compatibility of the adhesives ethylcyanoacrylate (Super Bonder) and butyl-cyanoacrylate (Histoacryl), and to compare the reparation of incisions in the dorsum of rats with suture and the respective adhesives. METHODS: Fifteen rats were used. Two surgical pockets were created in their dorsum. A polyethylene tube (10mm x 1mm) was implanted in each one. Each tube was filled with the adhesives Super Bonder (left side) and Histoacryl (right side). The incisions on the left side were closed with Super Bonder, and the incisions on the right side, with Histoacryl. A median incision between the two other incisions was made and closed with braided silk suture. The animals were killed after, 7, 35 and 120 days. RESULTS: The adhesives used in the present study did not promote inflammatory reaction when used for the synthesis of incisions. However, when implanted subcutaneously, they caused an inflammatory reaction within 120 days. Reaction is more severe with Histoacryl. CONCLUSIONS: Super Bonder and Histoacryl can be used effectively in the healing of incised tissues; they aid in the suture of incisions. However, these adhesives can be used for the synthesis of wounds, lacerations or cutaneous incisions.

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Comparison of Tensile Strength of Cyanoacrylate Tissue Adhesive Closure of Lacerations Versus Suture Closure

Cited by 40 publications

References 7 publications

Late Follow-Up of Cyanoacrylate Usage in Cardiothoracic Surgery

Late Follow-Up of Cyanoacrylate Usage in Cardiothoracic Surgery

Incised surgical wound closure with sutures and staples: a controlled experimental study

Adesivos à base de cianoacrilato para síntese de tecido mole

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