2009
DOI: 10.1007/s11695-009-9850-6
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Comparison of the Absorption of Calcium Carbonate and Calcium Citrate after Roux-en-Y Gastric Bypass

Abstract: Introduction Roux-en-Y gastric bypass (RYGB) restricts food intake. Consequently, patients consume less calcium. In addition, food no longer passes through the duodenum, the main site of calcium absorption. Therefore, calcium absorption is significantly impaired. The goal of this study is to compare two common calcium supplements in gastric bypass patients. Method Nineteen patients were enrolled in a randomized, double-blinded, crossover study comparing the absorption of calcium from calcium carbonate and ca… Show more

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Cited by 103 publications
(53 citation statements)
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“…Because calcium carbonate is more dependent on gastric acid secretion than calcium citrate, 1.5 g/d of calcium citrate (not calcium carbonate) is the preferred supplement. 13 Folate is not stored in the body in significant levels because it is a water-soluble vitamin. Folate deficiency is associated with macrocytic anemia, leukopenia, thrombocytopenia, glossitis, and elevated homocysteine levels.…”
Section: Which One Of the Following Nutritionalmentioning
confidence: 99%
“…Because calcium carbonate is more dependent on gastric acid secretion than calcium citrate, 1.5 g/d of calcium citrate (not calcium carbonate) is the preferred supplement. 13 Folate is not stored in the body in significant levels because it is a water-soluble vitamin. Folate deficiency is associated with macrocytic anemia, leukopenia, thrombocytopenia, glossitis, and elevated homocysteine levels.…”
Section: Which One Of the Following Nutritionalmentioning
confidence: 99%
“…Currently, the dominant anions in the calcium supplement market worldwide are carbonate and citrate [24]. It has been reported that calcium as citrate is better absorbed than calcium as carbonate, causing a greater rise in serum calcium and a greater fall in serum parathyroid hormone (PTH) [25,26]. Moreover, calcium as citrate is absorbed regardless of gastric acidity; thus, persons producing less gastric acids or receiving drugs that lower acidity in the stomach, like proton pump inhibitors [27], H 2 blockers, antacids and anticholinergics, may utilise this salt form optimally.…”
Section: Introductionmentioning
confidence: 99%
“…Previous studies have shown that CaCitrMalt is likely to be more bioavailable than CaCarb [8,21,22]. These differences arise from the dependency of CaCarb solubility on an acidic environment, while CaCitrMalt has been shown to be partially soluble in water [23].…”
Section: Discussionmentioning
confidence: 99%