Comparison of the accuracy of three early warning scores with SOFA score for predicting mortality in adult sepsis and septic shock patients admitted to intensive care unit

Khwannimit, Bodin; Bhurayanontachai, Rungsun; Vattanavanit, Veerapong

doi:10.1016/j.hrtlng.2019.02.005

Cited by 57 publications

(42 citation statements)

References 25 publications

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“…Recent studies have reported that SOFA is a useful tool in condition evaluation and prognosis prediction in patients with sepsis and it is also a widely used tool in prognosis and condition assessment in other critically ill patients. Bodin Khwannimit's study on 1589 patients with sepsis showed that SOFA score was a good predictor of 30-d and in-hospital mortality among patients with sepsis in the ICU and reported an AUC of 0.88 [30]. In Ming-Chin Yu's study, the SOFA score was found to be reliable in predicting mortality in severe acute pancreatitis with a reported AUC of 0.76 [16].…”

Section: Discussionmentioning

confidence: 98%

SOFA score is superior to APACHE-II score in predicting the prognosis of critically ill patients with acute kidney injury undergoing continuous renal replacement therapy

et al. 2020

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Background: Acute kidney injury (AKI) is the most common cause of organ failure in multiple organ dysfunction syndrome (MODS) and is associated with increased mortality. This study aimed at determining the efficacy of sequential organ failure assessment (SOFA), and acute physiology and chronic health evaluation II (APACHE-II) scoring systems in assessing the prognosis of critically ill patients with AKI undergoing continuous renal replacement therapy (CRRT). At present, APACHE-II score and SOFA score were also used to evaluate and predict the prognosis of critically ill patients with AKI. Methods: The predictive value of SOFA and APACHE-II scores for 28-and 90-d mortality in patients with AKI undergoing CRRT were determined by multivariate analysis, sensitivity analysis, and curve-fitting analysis. Results: A total of 836 cases were included in this study. Multivariate Cox logistic regression analysis showed that SOFA scores were associated with 28-and 90-d mortality in patients with AKI undergoing CRRT.

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Section: Discussionmentioning

confidence: 98%

SOFA score is superior to APACHE-II score in predicting the prognosis of critically ill patients with acute kidney injury undergoing continuous renal replacement therapy

et al. 2020

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“…EWSs are tools that assist in the clinical decision-making process and are implemented in Intensive Care Units (ICUs), non-ICU settings, ED and more recently in pre-hospital care or even nursing homes [13][14][15]. The advantage of this type of score is the possibility of early detection of the risk of clinical deterioration, which has facilitated its use in multiple health systems, with a global implementation [16][17][18].…”

Section: Introductionmentioning

confidence: 99%

Early Warning Scores in Patients with Suspected COVID-19 Infection in Emergency Departments

Martin-Rodríguez

Conty

Sanz-García

et al. 2021

JPM

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Early warning scores (EWSs) help prevent and recognize and thereby act as the first signs of clinical and physiological deterioration. The objective of this study is to evaluate different EWSs (National Early Warning Score 2 (NEWS2), quick sequential organ failure assessment score (qSOFA), Modified Rapid Emergency Medicine Score (MREMS) and Rapid Acute Physiology Score (RAPS)) to predict mortality within the first 48 h in patients suspected to have Coronavirus disease 2019 (COVID-19). We conducted a retrospective observational study in patients over 18 years of age who were treated by the advanced life support units and transferred to the emergency departments between March and July of 2020. Each patient was followed for two days registering their final diagnosis and mortality data. A total of 663 patients were included in our study. Early mortality within the first 48 h affected 53 patients (8.3%). The scale with the best capacity to predict early mortality was the National Early Warning Score 2 (NEWS2), with an area under the curve of 0.825 (95% CI: 0.75–0.89). The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive patients presented an area under the curve (AUC) of 0.804 (95% CI: 0.71–0.89), and the negative ones with an AUC of 0.863 (95% CI: 0.76–0.95). Among the EWSs, NEWS2 presented the best predictive power, even when it was separately applied to patients who tested positive and negative for SARS-CoV-2.

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“…Lie et al [30] reported that the overall 28-day mortality rate in patients with sepsis and severe sepsis was 22%; rates ranged from 7% for those with a SOFA score of 2 to 39% for those with scores > 6 at the time of ICU admission. Khwannimit et al [31] reported that the overall 30-day mortality rate for patients with septic shock and a SOFA score of 9 was 45.1%. In our study, the mean SOFA score before HA330 hemoperfusion was 10.52 ± 4.59, and the rate of mortality in the ICU was 39.1% (Tables 1, 6).…”

Section: Discussionmentioning

confidence: 99%

Efficacy of HA330 Hemoperfusion Adsorbent in Patients Followed in the Intensive Care Unit for Septic Shock and Acute Kidney Injury and Treated with Continuous Venovenous Hemodiafiltration as Renal Replacement Therapy

et al. 2020

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Introduction: Blood purification is an option for treatment of the source of sepsis when correcting patients' septic shock-induced clinical status. We investigated the efficacy of HA330 hemoperfusion adsorbent application with renal replacement therapy in patients with septic shock and acute kidney injury. Methods: This prospective observational study involved 23 patients diagnosed with sepsis who underwent continuous venovenous hemodiafiltration and HA330 hemoperfusion for 2 h once daily for 3 days. The patients' demographic data, comorbidities, lengths of intensive care unit and hospital stays, blood cell counts, blood biochemistry values, coagulation values, blood gas values, inflammatory markers, hemodynamic parameters, and inotropic medication use before and after each application of HA330 hemoperfusion were recorded. The effectiveness of HA330 hemoperfusion was evaluated by comparing the parameters on days 0 and 1, 1 and 2, and 2 and 3. Results: The pH increased significantly following the first application of HA330 hemoperfusion (p = 0.001), the C-reactive protein (CRP) and procalcitonin levels decreased significantly after the second application (p = 0.002 and 0.018, respectively), and the CRP level decreased significantly following the third application (p = 0.046). Conclusions: The application of HA330 hemoperfusion 2 h daily for 3 consecutive days improved level of CRP and heart rate, but had no effect on others or on the prognosis.

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Comparison of the accuracy of three early warning scores with SOFA score for predicting mortality in adult sepsis and septic shock patients admitted to intensive care unit

Cited by 57 publications

References 25 publications

SOFA score is superior to APACHE-II score in predicting the prognosis of critically ill patients with acute kidney injury undergoing continuous renal replacement therapy

SOFA score is superior to APACHE-II score in predicting the prognosis of critically ill patients with acute kidney injury undergoing continuous renal replacement therapy

Early Warning Scores in Patients with Suspected COVID-19 Infection in Emergency Departments

Efficacy of HA330 Hemoperfusion Adsorbent in Patients Followed in the Intensive Care Unit for Septic Shock and Acute Kidney Injury and Treated with Continuous Venovenous Hemodiafiltration as Renal Replacement Therapy

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