“…The characteristics and distribution of the CD34+SCs/TCs around apparently unaffected skin vessels and appendages in early KS lesions agree with those previously described in several conditions [ 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 ], creating microenvironments within the tissues (a contribution to maintenance and modulation of local homeostasis) [ 21 , 31 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 ]. Likewise, the ability of CD34+SCs/TCs to envelop perivascular inflammatory infiltrates in KS is also consistent with their role in retaining and modulating the immune cells [ 31 , 53 , 54 , 55 , 56 , 57 ], allowing us to explain the presence of an inflammatory component around some intussusceptive pre-existing blood vessels within neovessels (vessels into vessels: a promontory sign in KS).…”