Comparison of the biometric parameters in patients with high myopia and anisometropia

Abstract

Background To compare biometric parameters, especially lens parameters, in patients with high myopia and anisometropia. Methods Patients with spherical equivalent greater than -6D and at least one eye with an axial length greater than 26 mm and a difference in binocular axial length greater than 2 mm were included in this study. In each patient, the eye with a relatively shorter axial length was assigned to Group S, and the other eye was assigned to Group L. In patients whose binocular axial length difference was greater than 4 mm, the eye with the shorter axial length was assigned to Group S1 and the other eye was assigned to Group L1. In patients whose shorter eye axial was less than 26 mm, the eye with the shorter axial was assigned to Group S2 and the other eye was assigned to Group L2. Central corneal thickness, corneal curvature radius, axial length, anterior chamber depth, lens thickness, white-to-white corneal diameter and the radius of the anterior and posterior lens capsules were compared between Group S and Group L, Groups S1 and L1, and Groups S2 and L2. Results Sixty-four people were enrolled in the study. There were 26 people with an axial length difference more than 4 mm (Group S1 and Group L1) and 34 patients with an axial length less than 26 mm (Group S2 and Group L2). No significant differences were found in any parameters except axial length between Group S and Group L, Groups S1 and L1, or Groups S2 and L2 (p > 0.05). Conclusions The anterior parameters of patients with high myopia did not change with the axial length.

Comparative analysis of corneal parameters in simple myopic anisometropia using Scheimpflug technology

“…Consequently, the correlation with AL diminishes ( Liu et al, 2021 ; Sedaghat et al, 2021 ). Liu et al ( Liu J. et al, 2022 ) observed no significant differences in ACD, CCT, Km, and LT among highly myopic eyes with anisometropia. Furthermore, Liu et al ( Liu et al, 2021 ) reported a lack of significant correlation between SSI and AL in eyes with severe axial elongation (AL≥26 mm), suggesting a non-linear influence of AL on corneal parameters.…”

“…It is important to note that AL elongation tends to be relatively uniform during the physiological progression of myopia. However, in cases of pathological myopia, the extension is primarily concentrated at the posterior pole, with anterior structural changes remaining relatively stable ( Liu J. et al, 2022 ). Consequently, the correlation with AL diminishes ( Liu et al, 2021 ; Sedaghat et al, 2021 ).…”

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“…The rapid increase in the myopia population has become a global public health problem [1] . High myopia is usually defined as spherical refractive errors less than -6.00 diopters (D) or ocular axial length (AL) more than 26 mm [2] . Elongation of the AL and thinning of the retina, which often cause a series of degenerative changes in the fundus of pathological myopia, such as fundus tessellation (FT), temporal peripapillary chorioretinal atrophy, posterior scleral staphyloma, lacquer crack, myopic retinoschisis, and macular degeneration, is one of the common causes of blindness in China [3][4] .…”