Comparison of the Coadsorption of Benzyl Alcohol and Phenyl Ethanol with the Cationic Surfactant, Hexadecyl Trimethyl Ammonium Bromide, at the Air–Water Interface

Penfold, J.; Staples, E.; Tucker, I.; Soubiran, L.; Thomas, Robert K.

doi:10.1006/jcis.2001.8041

Cited by 16 publications

(26 citation statements)

References 25 publications

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“…Besides sublethal heat stress or various concentrations of BA, B16(F10) cells were exposed to the slightly more hydrophobic analog of BA, PhA (22). Surprisingly, if applied at the concentration equipotent in membrane fluidization with BA, monitored at a distinct membrane depth, PhA was shown to be ineffective as an hsp activator.…”

Section: Discussionmentioning

confidence: 99%

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Hyperfluidization-coupled membrane microdomain reorganization is linked to activation of the heat shock response in a murine melanoma cell line

Nagy

Balogi

Gombos

et al. 2007

Proc. Natl. Acad. Sci. U.S.A.

105

126

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Targeting of the Hsp function in tumor cells is currently being assessed as potential anticancer therapy. An improved understanding of the molecular signals that trigger or attenuate the stress protein response is essential for advances to be made in this field. The present study provides evidence that the membrane fluidizer benzyl alcohol (BA), a documented nondenaturant, acts as a chaperone inducer in B16(F10) melanoma cells. It is demonstrated that this effect relies basically on heat shock transcription factor 1 (HSF1) activation. Under the conditions tested, the BA-induced Hsp response involves the up-regulation of a subset of hsp genes. It is shown that the same level of membrane fluidization (estimated in the core membrane region) attained with the closely analogous phenethyl alcohol (PhA) does not generate a stress protein signal. BA, at a concentration that activates heat shock genes, exerts a profound effect on the melting of raft-like cholesterolsphingomyelin domains in vitro, whereas PhA, at a concentration equipotent with BA in membrane fluidization, has no such effect. Furthermore, through the in vivo labeling of melanoma cells with a fluorescein labeled probe that inserts into the cholesterol-rich membrane domains [fluorescein ester of polyethylene glycol-derivatized cholesterol (fPEG-Chol)], we found that, similarly to heat stress per se, BA, but not PhA, initiates profound alterations in the plasma membrane microdomain structure. We suggest that, apart from membrane hyperfluidization in the deep hydrophobic region, a distinct reorganization of cholesterol-rich microdomains may also be required for the generation and transmission of stress signals to activate hsp genes. molecular chaperones ͉ stress signaling ͉ membrane defects ͉ rafts ͉ cancer therapy

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Section: Discussionmentioning

confidence: 99%

“…3A). Compared with BA, the slightly more hydrophobic PhA (22) proved to be a more effective membrane fluidizer (Fig. 3A).…”

Section: Comparative Analysis Of the Promoter Region Of Heat-induciblmentioning

confidence: 97%

Hyperfluidization-coupled membrane microdomain reorganization is linked to activation of the heat shock response in a murine melanoma cell line

Nagy

Balogi

Gombos

et al. 2007

Proc. Natl. Acad. Sci. U.S.A.

105

126

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“…In previous experiments on C 16 TAB/C 12 E 6 at the water/air interface [18] it was observed that the volume fraction profiles of both molecules coincide for lower C 12 E 6 concentrations. In experiments on benzyl alcohol with C 16 TAB at the air/water interface, it was observed that the relative positions of the volume fraction distributions are not too different [37]. Also, experiments on C 16 TAB and C 12 E 6 show similar positions of the volume fraction distribution at the air/water interface for both surfactants [38].…”

Section: Density Profile Head Group and Hydrocarbon Chain Lengthmentioning

confidence: 92%

Computer simulation studies of surfactant monolayer mixtures at the water/oil interface: charge distribution effects

Domínguez

2004

Journal of Colloid and Interface Science

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“…The measurements were made at a constant temperature of 25°C and the samples (with a total volume $25 ml) were contained in stainless steel troughs. Previous measurements in Teflon troughs [30] have established that preferential adsorption of the perfume components to the Teflon surface can substantially affect the adsorption to the air-water interface. The measurements were made initially for the LAS-6/CaCl 2 mixture, and when the surface multilayer structure reached equilibrium (after $60 to 90 min) the perfume was added progressively using a micro-pipette.…”

Section: Neutron Reflectivitymentioning

confidence: 99%

Enhanced perfume surface delivery to interfaces using surfactant surface multilayer structures

Bradbury¹,

Penfold

Thomas³

et al. 2016

Journal of Colloid and Interface Science

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Enhanced surface delivery and retention of perfumes at interfaces are the keys to their more effective and efficient deployment in a wide range of home and personal care related formulations. It has been previously demonstrated that the addition of multivalent counterions, notably Ca(2+), induces multilayer adsorption at the air-water interface for the anionic surfactant, sodium dodecyl-6-benzenesulfonate, LAS-6. Neutron reflectivity, NR, measurements are reported here which demonstrate that such surfactant surface multilayer structures are a potentially promising vehicle for enhanced delivery of perfumes to interfaces. The data show that the incorporation of the model perfumes, phenylethanol, PE, and linalool, LL, into the surface multilayer structure formed by LAS-6/Ca(2+) results in the surface structures being retained up to relatively high perfume mole fractions. Furthermore the amount of perfume at the surface is enhanced by at least an order of magnitude, compared to that co-adsorbed with a surfactant monolayer.

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Comparison of the Coadsorption of Benzyl Alcohol and Phenyl Ethanol with the Cationic Surfactant, Hexadecyl Trimethyl Ammonium Bromide, at the Air–Water Interface

Cited by 16 publications

References 25 publications

Hyperfluidization-coupled membrane microdomain reorganization is linked to activation of the heat shock response in a murine melanoma cell line

Hyperfluidization-coupled membrane microdomain reorganization is linked to activation of the heat shock response in a murine melanoma cell line

Computer simulation studies of surfactant monolayer mixtures at the water/oil interface: charge distribution effects

Enhanced perfume surface delivery to interfaces using surfactant surface multilayer structures

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