Comparison of the diagnostic performances of diffusion parameters in diffusion weighted imaging and diffusion tensor imaging of breast lesions

Diffusion tensor imaging of breast lesions: evaluation of apparent diffusion coefficient and fractional anisotropy and tissue cellularity

“…In our study, the mean FA value of breast cancers was significantly higher than that of benign lesions, which is in accordance with the result of Baltzer et al 10 but contrary to that of Cakir et al 8 As our study showed, there seemed to be a rising tendency in FA values with the increase of malignancy and grade of breast tumours (Table 3); but, the FA values between DCIS and IDC had no statistical difference. It suggests that the difference in the FA among different kinds of breast lesions may be small and FA alone is unable to distinguish different grades of breast tumours.…”

“…The mean ADC values of breast cancer and the cellularity in the two groups were in accordance with the previous studies. 8,13 The results also showed that ADC values of breast cancers were statistically lower than that of benign lesions (p , 0.001). However, there are some overlaps between benign and malignant diseases in our study and previous literature, which may influence the diagnosis and differentiation of breast cancers.…”

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

“…More recently, diffusion weighted MRI and the resulting maps of apparent diffusion coefficient (ADC) have been evaluated as a complement method to DCE-MRI and it was shown that ADC values can help distinguish between cancers, benign lesions and normal breast tissue 9,10 . In addition, studies of breast diffusion tensor imaging (DTI) were initiated in healthy volunteers and patients with breast lesions at field strength of 1.5 T [11][12][13][14][15] and of 3 T [16][17][18][19][20][21][22][23][24] . Most of these studies reported ADC and fractional anisotropy (FA) values 11,12,14,15,[20][21][22][23] and found these two parameters to be reproducible with ADC values more reproducible than FA 13,20 .…”

“…In addition, studies of breast diffusion tensor imaging (DTI) were initiated in healthy volunteers and patients with breast lesions at field strength of 1.5 T [11][12][13][14][15] and of 3 T [16][17][18][19][20][21][22][23][24] . Most of these studies reported ADC and fractional anisotropy (FA) values 11,12,14,15,[20][21][22][23] and found these two parameters to be reproducible with ADC values more reproducible than FA 13,20 . The results of these studies indicated that malignant lesions exhibit low ADC values as compared to normal tissue and benign lesions, however, conflicting results were reported on the values and diagnostic capability of FA 11,12,14,[20][21][22][23] .…”

“…Most of these studies reported ADC and fractional anisotropy (FA) values 11,12,14,15,[20][21][22][23] and found these two parameters to be reproducible with ADC values more reproducible than FA 13,20 . The results of these studies indicated that malignant lesions exhibit low ADC values as compared to normal tissue and benign lesions, however, conflicting results were reported on the values and diagnostic capability of FA 11,12,14,[20][21][22][23] . In a set of 3 T-DTI studies the values of the three tensor eigenvalues and eigenvectors in the breast tissue frame were reported as well, and the results were presented in vector maps of the main eigenvector and parametric maps of the eigenvalues, ADC, FA and a maximal anisotropy index [16][17][18][19]24 .…”