Comparison of the dosimetry and cell survival effect of 177Lu and 161Tb somatostatin analog radiopharmaceuticals in cancer cell clusters and micrometastases
Laura De Nardo,
Sara Santi,
Anna Dalla Pietà
et al.
Abstract:Background
177
Lu-based radiopharmaceuticals (RPs) are the most used for targeted radionuclide therapy (TRT) due to their good response rates. However, the worldwide availability of
177
Lu is limited.
161
Tb represents a potential alternative for TRT, as it emits photons for SPECT imaging, β
−
-particles for therapy, and also releases a significant yield of internal conversion (IE) and Auger electrons (… Show more
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