2013
DOI: 10.1111/pde.12118
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Comparison of the Effect of Human Milk and Topical Hydrocortisone 1% on Diaper Dermatitis

Abstract: Diaper dermatitis is one of the most common skin problems in infants and children, affecting between 7% and 35% of infants. This randomized clinical trial compared the efficacy of hydrocortisone 1% ointment with that of human breast milk in treating acute diaper dermatitis in infants ages 0 to 24 months. Infants with diaper rash were treated with either hydrocortisone 1% ointment (n = 70) or human breast milk (n = 71) for 7 days. Improvement in the rash from baseline was seen in both treatment groups on days 3… Show more

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Cited by 32 publications
(38 citation statements)
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“…The milk microbiome can influence commensal oral and gut infant bacteria but also their skin microbiota. There are a few reports on the topical application of human milk as an effective treatment for diaper rash, atopic eczema, diaper dermatitis or umbilical cord separation [5052]. Generally, human milk can be easy, cheap, safe and non-invasive therapeutic approach.…”
Section: Discussionmentioning
confidence: 99%
“…The milk microbiome can influence commensal oral and gut infant bacteria but also their skin microbiota. There are a few reports on the topical application of human milk as an effective treatment for diaper rash, atopic eczema, diaper dermatitis or umbilical cord separation [5052]. Generally, human milk can be easy, cheap, safe and non-invasive therapeutic approach.…”
Section: Discussionmentioning
confidence: 99%
“…When locally applied to the irritated area, it alleviated inflammation and limited progression of skin lesions [18]. It was also shown, that therapeutic efficacy of breast milk was comparable to 1% hydrocortisone ointment with significant improvement in skin condition [19]. However, this study was conducted on a small group of patients.…”
Section: Discussionmentioning
confidence: 86%
“…Topical corticosteroids are still recognized as a treatment option for diaper dermatitis, although it is increasingly discouraged. 25 Farahani et al and Gozen et al described human breast milk as an effective and safe treatment for diaper dermatitis in infants, 11,26 whereas Spraker et al recommended topical miconazole nitrate ointment for the treatment of diaper dermatitis. 27 …”
Section: Discussionmentioning
confidence: 99%