Comparison of the effectiveness of extensor muscle strengthening exercise by itself, exercise with polydeoxyribonucleotide injection, and exercise with extracorporeal shockwave therapy in lateral epicondylitis: a randomized controlled trial

Shim, Bum-Jin; Seo, Eun-Min; Hwang, Jung-Taek; Kim, Doyoung; Yang, Jae-Shin; Seo, Su-Jung; Hong, Misun

doi:10.5397/cise.2021.00290

Cited by 9 publications

(6 citation statements)

References 14 publications

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“…After combining selected studies to estimate the precise effect of ESWT on the crude average pain score in patients with LE, the results showed that, overall, the average pain in these patients decreased by 0.63 units based on the crude score of the VAS tool. While the diagnosis of LE is usually straightforward, its treatment presents several challenges [ 49 , 129 , 130 ].…”

Section: Discussionmentioning

confidence: 99%

The effect of extracorporeal shock-wave therapy on pain in patients with various tendinopathies: a systematic review and meta-analysis of randomized control trials

Majidi,

Khateri,

Nikbakht

et al. 2024

BMC Sports Sci Med Rehabil

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Objectives Tendinopathy is a common condition that affects the body’s tendon structures, causing discomfort, restricted movement, and reduced functionality. In this study, we looked at how extracorporeal shock wave therapy (ESWT) affected pain levels in individuals with various forms of tendinopathy around the world. Design This study is a comprehensive review and meta-analysis of previously published randomized controlled trials. To gather relevant data, the researchers performed keyword searches in international databases, including PubMed (Medline), Scopus, Web of Sciences, Cochrane Central Register of Controlled Trials (CENTRAL), Research Registers of ongoing trials (ClinicalTrials.gov), as well as Embase. The search was conducted up until March 2023. The quality of the selected articles was assessed using the Cochrane risk-of-bias method for randomized trials (RoB2). Results Based on the results of the meta-analysis, which included 45 clinical studies, the use of ESWT was found to have a significant impact on reducing pain in various conditions. The standardized mean difference (SMD) in patients with plantar fasciitis (PF) was reduced by 1.63 (SMD: -1.63, 95% CI: -3.04, -0.21; I2: 77.36%; P heterogeneity: 0.0001). For lateral epicondylitis (LE), the SMD was 0.63 (SMD: -0.63, 95% CI: -1.11, -0.16; I2: 67.50%; P heterogeneity: 0.003). In the case of chronic Achilles tendinopathy, the SMD was 1.38 (SMD: -1.38, 95% CI: -1.66, -1.10; I2: 96.44%; P heterogeneity: 0.0001). Additionally, in individuals with rotator cuff tendinopathy, the SMD for pain reduction was 2.37 units (SMD: -2.37, 95% CI: -3.58, -1.15; I2: 98.46%; P heterogeneity: 0.0001). Conclusion This study suggests that ESWT can be a highly effective therapy option for relieving pain in people with tendinopathy. Nonetheless, it is encouraged to make additional recommendations based on high-quality clinical research and more accurate information in order to define the optimal therapeutic options for each type of tendinopathy.

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Section: Discussionmentioning

confidence: 99%

The effect of extracorporeal shock-wave therapy on pain in patients with various tendinopathies: a systematic review and meta-analysis of randomized control trials

Majidi,

Khateri,

Nikbakht

et al. 2024

BMC Sports Sci Med Rehabil

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“…PRP injections have been used, yielding mixed results-promising according to some studies, but less so in others [25][26][27]. Additionally, polydeoxyribonucleotide injections are a consideration, particularly since a combination of polydeoxyribonucleotide injections and exercises to strengthen the extensor muscles showed superior improvement in functional scores when compared to exercises alone or exercises combined with extracorporeal shock wave therapy (ESWT) [31].…”

Section: Lateral Elbow Painmentioning

confidence: 99%

Recent Nonoperative Treatment of Elbow Pain

Han,

Jeon

2023

Ewha Med J

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Pain originating from the elbow can be due to issues affecting the joint itself or the structures surrounding it. These structures include the medial and lateral epicondyles, associated ligaments, the origins of wrist flexor and extensor muscles, the olecranon bursa, the distal biceps tendon, and the radial and ulnar nerves. Pain that appears to originate from a different location may actually be referred pain, potentially stemming from the neck (cervical radiculopathy) or the shoulder. Among complaints related to the elbow, lateral elbow pain is the most frequently reported. This pain could originate from the lateral epicondyle, the radiohumeral joint, or it could be referred pain from other areas. Medial elbow pain is the second most common complaint, often resulting from issues with the medial epicondyle or the ulnar nerve as it travels through the cubital tunnel. The biceps tendon is frequently the cause of anterior elbow pain. Patients who report swelling in the elbow are often experiencing olecranon bursitis. These conditions can often be effectively managed through conservative treatment. The aim of this article is to provide a structured approach to addressing patients with elbow pain, by detailing the common causes of such discomfort and exploring effective nonsurgical treatment options.

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“…If epicondylitis remains unimproved after 3 to 6 months of treatment, it is considered refractory and surgical intervention may be indicated. Conservative treatment encompasses exercise therapy, physical therapy, drug therapy, bracing, extracorporeal shock wave therapy, percutaneous pie crusting of the tendon origin [9] polydeoxyribonucleotide injections [10], platelet-rich plasma (PRP) injections [11], autologous blood injections [12], and local corticosteroid injection therapy.…”

Section: )Medialepicondylitismentioning

confidence: 99%