Comparison of the effects of inosine and inosine monophosphate on growth, immune response, stress resistance and gut morphology of juvenile red sea bream, Pagrus major

Effects of dietary administration of guanosine monophosphate on the growth, digestibility, innate immune responses and stress resistance of juvenile red sea bream, Pagrus major

“…This observation is in agreement with the previous findings of Lin et al [16] who reported that nucleotide GMP significantly increased the growth performance of grouper (E. malabaricus). Similarly the growth enhancing effects of some other individual and mixed nucleotides have also been reported in some previous studies [24,25,36,37]. So far, there is no exact explanation of how dietary nucleotide works to enhance growth.…”

“…Borda et al [38] presumed that an exogenous supply of nucleotides may promote growth of fish and crustaceans in early stages to meet their high rate of cell replication. However, it is assumed that the growth-enhancing effect of GMP in the present study resulted from improved feed intake (Table 3), promoting more rapid feed intake that reduced nutrient leaching into the water or possibly playing roles in metabolism [25,39]. To improve the dietary value of supplemental nucleotide GMP, reducing the leaching loss of GMP into water is important.…”

“…Since the first use of nucleotide in aquaculture, a growing number of studies have demonstrated that nucleotides act as an immunomodulators as well as a functional nutrient in fish and shrimp [13,25,26,36,37], in which mixed nucleotides were commonly used in those studies. To our knowledge, this study was the first study to investigate the effects of GMP as individual nucleotide as well as a potential functional nutrient for red sea bream juveniles.…”

“…However, research on dietary modulation for potential growth and health management of this species is very scarce. Recently, we evaluated the functional effects of IMP, inosine and mixed nucleotide on this species [24,25]. However, to the best of our knowledge there is no research on individual nucleotide GMP as feeding stimulant as well as a functional nutrient for potential growth and health benefit of red sea bream Therefore, the present study was conducted to assess the effects of dietary administration of GMP on the growth, digestibility, immune responses and stress resistance of juvenile red sea bream, Pagrus major.…”

Acute metabolic response of Portunus trituberculatus to Vibrio alginolyticus infection

“…b A, 0 h control crab; B, 24 h control crab; C, virus-infected crab. that IMP has an enhancement to the growth performance, survival, immune response, and disease defense of different aquatic species such as olive flounder and red sea bream (Hossain et al, 2016). Immunostimulating properties of IMP enable fishes to have an increased bactericidal activity Hossain et al, 2016).…”