Comparison of the effects of colloid preload, vasopressor administration and leg compression on hemodynamic changes during spinal anesthesia for lumbar disc surgery in knee–chest position

Fani, Abdolrahman; Hirmanpour, Anahita

doi:10.4103/2277-9175.164002

Adv Biomed Res

2015

DOI: 10.4103/2277-9175.164002

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Comparison of the effects of colloid preload, vasopressor administration and leg compression on hemodynamic changes during spinal anesthesia for lumbar disc surgery in knee–chest position

Abdolrahman Fani

Anahita Hirmanpour

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Cited by 2 publications

References 13 publications

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A comparative study between intravenous Ondansetron and Granisetron in attenuation of hypotension during spinal anaesthesia in patients undergoing caesarean section

Anisha¹,

Narayan²

2020

IJCA

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Hypotension is most common intraoperative complication after spinal anesthesia during cesarean delivery. The Bezold-Jarisch reflex is one of the causes for occurrence of hypotension after spinal anesthesia through serotonin with decreased blood volume. Our aim of this study was to compare the two serotonin receptor antagonists Ondansetron and Granisetron to prevent spinal induced hypotension and bradycardia after spinal anesthesia in parturients undergoing cesarean sections. Materials and Methods: 90 patients of ASA class-I and II, aged 20-40years, weight 40-80kilograms were included in this study. Patient with history of PIH, convulsion, any major comorbidity were excluded from study. Patients were assigned into 3 groups group A received 4 mg Ondansetron intravenously, group B received 1 mg Granisetron intravenously and group C received 10 ml of intravenous normal saline 5 min before spinal anaesthesia. The difference in mean was analyzed using post hoc Bonferroni test and ANOVA test. The difference in proportions was analyzed by using chi-square test. Results: SBP, DBP and MBP were statistically lower in both Granisetron and Saline group as compared to Ondansetron group at most of the times after drug administration. Heart rate and shivering were comparable in the three groups. Nausea and vomiting was statistically more in saline group as compared to other groups. Use of ephedrine was also significantly more in saline group (37%). Conclusion: 4mg intravenous Ondansetron prior to spinal anaesthesia in LSCS patients reduces the incidence of hypotension, bradycardia and need of vasopressor. Granisetron had no effect on haemodynamic parameters.

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A comparative study between intravenous Ondansetron and Granisetron in attenuation of hypotension during spinal anaesthesia in patients undergoing caesarean section

Anisha¹,

Narayan²

2020

IJCA

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Comparison between colloid preload and coload in bone cement implantation syndrome under spinal anesthesia: A randomized controlled trial

Özcan¹,

Kesimci²,

Balci

et al. 2018

Anesth Essays Res

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Comparison of the effects of colloid preload, vasopressor administration and leg compression on hemodynamic changes during spinal anesthesia for lumbar disc surgery in knee–chest position

Cited by 2 publications

References 13 publications

A comparative study between intravenous Ondansetron and Granisetron in attenuation of hypotension during spinal anaesthesia in patients undergoing caesarean section

A comparative study between intravenous Ondansetron and Granisetron in attenuation of hypotension during spinal anaesthesia in patients undergoing caesarean section

Comparison between colloid preload and coload in bone cement implantation syndrome under spinal anesthesia: A randomized controlled trial

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