“…Nilvadipine is currently licensed as an antihypertensive agent and has a better tolerability profile than nitrendipine, amlodipine or nifedipine, despite similar efficacy for reducing BP in hypertensive individuals (Faust, 1992;Keck, 1992;Leonetti, 2005). However, the treatment of normotensive individuals with nilvadipine might cause an undesired reduction in BP and/or orthostatic hypotension (OH), particularly in AD patients many of whom have impaired cerebrovascular responses and are already prone to hypotension (Allan et al, 2007;Schuff et al, 2009).…”