Comparison of the Hemodynamic Effects of Two Drugs Thiopental Sodium and Propofol in Patients Undergoing Electroconvulsive Therapy, RCT

Abstract

Background: Electroconvulsive Therapy (ECT) in the treatment of mental illnesses and the importance of using an anesthesia method that causes the least hemodynamic changes in the patient, we decided to evaluate their effects in this case with both thiopental sodium and propofol.Aim: This study aimed to compare the hemodynamic effects of the drug, sodium thiopental and propofol common among the anesthetic agent may be, in patients treated with ECT is done. Materials and Methods:This study hospital 22 Bahman in Qazvin on 84 patients in two groups (42 patients in thiopental sodium group and 42 patients in propofol group) electroconvulsive brain under general anesthesia by propofol and thiopental has been carried out. Hemodynamic changes in systolic and diastolic blood pressure (mm mmHg) and pulse rate, number of minutes, duration of seizure and recovery time (min) size were recorded.Result: measuring blood pressure and pulse before and after anesthesia and ECT show that, in patients in thiopental sodium group changes in systolic blood pressure, diastolic and pulse rate. Respectively 45% and 64% and 26% in the third minute of the study. In the propofol group, the highest systolic, diastolic blood pressure changes were 55% and 64% at the tenth minute, respectively, but the highest pulse rate increase was at the third minute and 33%, respectively. Test Friedman is also a significant relationship between consumption of these drugs, blood pressure showed that The duration of seizures during ECT sodium thiopental less than group B, but the duration of anesthesia with propofol shorter return is .The results were: Due to better hemodynamic stability of sodium thiopental, propofol, the drug is preferred to more.