Comparison of the platelet concentrations obtained in platelet-rich plasma (PRP) between the GPS™ II and GPS™ III systems

Kaux, Jean-François; Goff, Caroline Le; Renouf, Julien; Péters, Pierre; Lutteri, Laurence; Gothot, André; Crielaard, Jean-Michel

doi:10.1016/j.patbio.2010.11.002

Cited by 37 publications

(33 citation statements)

References 11 publications

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“…Varying the concentration of white blood cells within PRP is one factor influencing cell proliferation [336,337]. Different separation techniques also result in greatly varying concentrations of platelet-derived growth factors [329] and can vary greatly in the concentration of platelets by four-to ninefold [338]. In addition, regardless of the separation method used, even blood from different individuals has large variations in platelet and cell numbers and in the levels of various growth factors [337].…”

Section: Cautions In Using Prp: Prp Compositionmentioning

confidence: 99%

Platelet-Rich Plasma Promotes Axon Regeneration, Wound Healing, and Pain Reduction: Fact or Fiction

Kuffler

2015

Mol Neurobiol

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Platelet-rich plasma (PRP) has been tested in vitro, in animal models, and clinically for its efficacy in enhancing the rate of wound healing, reducing pain associated with injuries, and promoting axon regeneration. Although extensive data indicate that PRP-released factors induce these effects, the claims are often weakened because many studies were not rigorous or controlled, the data were limited, and other studies yielded contrary results. Critical to assessing whether PRP is effective are the large number of variables in these studies, including the method of PRP preparation, which influences the composition of PRP; type of application; type of wounds; target tissues; and diverse animal models and clinical studies. All these variables raise the question of whether one can anticipate consistent influences and raise the possibility that most of the results are correct under the circumstances where PRP was tested. This review examines evidence on the potential influences of PRP and whether PRP-released factors could induce the reported influences and concludes that the preponderance of evidence suggests that PRP has the capacity to induce all the claimed influences, although this position cannot be definitively argued. Well-defined and rigorously controlled studies of the potential influences of PRP are required in which PRP is isolated and applied using consistent techniques, protocols, and models. Finally, it is concluded that, because of the purported benefits of PRP administration and the lack of adverse events, further animal and clinical studies should be performed to explore the potential influences of PRP.

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Section: Cautions In Using Prp: Prp Compositionmentioning

confidence: 99%

Platelet-Rich Plasma Promotes Axon Regeneration, Wound Healing, and Pain Reduction: Fact or Fiction

Kuffler

2015

Mol Neurobiol

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“…Depending on how they are obtained and prepared, PRPs (or Platelet-Released Growth Factors PRGF) present highly variable concentrations of platelets [8][9][10] , erythrocytes and leukocytes. It is still necessary to optimize the techniques for obtaining and concentrating PRPs and standardizing the injection.…”

Section: Preparing Prpmentioning

confidence: 99%

Reflections about the optimisation of the treatment of tendinopathies with PRP

Kaux¹

2015

MLTJ

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SummaryBackground: platelet-rich plasma (PRP) infiltration represents a recent therapy for chronic tendinopathies. However, in the literature, this treatment remains controversial. Purpose: we suggest some ideas for improving this treatment. Methods: these suggestions were based on a review of published studies and our clinical experience. Conclusion: optimizing the technique for PRP collection is paramount. Different risk factors must be corrected before infiltration and chronic tendinopathies must be carefully selected. Finally, post-infiltration rehabilitation remains absolutely

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“…Other studies used two or three injections with saline injections in the control group 21,23 . PRP preparation methods, which affect PRP composition 24 , have varied across studies. We chose the Ortho.Pras 20 kit Proteal system.…”

Section: Discussionmentioning

confidence: 99%

Platelet-rich plasma (PRP) treatment of sports-related severe acute hamstring injuries

Guillodo

Madouas

Simon

et al. 2015

MLTJ

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SummaryPurpose: hamstring injury is the most common musculoskeletal disorder and one of the main causes of missed sporting events. Shortening the time to return to play (TTRTP) is a priority for athletes and sports medicine practitioners. Hypothesis: platelet-rich plasma (PRP) injection at the site of severe acute hamstring injury increases the healing rate and shortens the TTRTP. KEY WORDS: platelet-rich plasma (PRP), hamstring injury, return to play, muscle injury, management. What is known about the subjectLocal platelet-rich plasma (PRP) injection was introduced recently to expedite recovery from sports-related injuries. However, little evidence exists to support the effectiveness of PRP in shortening the time to return to play at the previous level after a hamstring injury. What this study adds to existing knowledgeOur cohort study of athletes with grade III acute hamstring injuries who accepted or refused PRP therapy (n=15 and n=19, respectively) found no evidence that a single local PRP injection (3 mL) shortened the TTRTP.

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Comparison of the platelet concentrations obtained in platelet-rich plasma (PRP) between the GPS™ II and GPS™ III systems

Cited by 37 publications

References 11 publications

Platelet-Rich Plasma Promotes Axon Regeneration, Wound Healing, and Pain Reduction: Fact or Fiction

Platelet-Rich Plasma Promotes Axon Regeneration, Wound Healing, and Pain Reduction: Fact or Fiction

Reflections about the optimisation of the treatment of tendinopathies with PRP

Platelet-rich plasma (PRP) treatment of sports-related severe acute hamstring injuries

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