Comparison of the prevalence of perforated appendicitis during and before COVID19 pandemic

Azadbakht, Morteza; Azadbakht, Saleh; Daniali, Samira; Dehghani, Maryam

doi:10.1016/j.amsu.2022.104785

Cited by 3 publications

(1 citation statement)

References 23 publications

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“…However, the age group of children with the most negative appendectomies was between 10 and 18 years, while the proportion of cases in children younger than 5 years was lower [42]. During the COVID-19 pandemic, the incidence of negative appendectomies reduced, but the incidence of complicated appendicitis compared to the pre-pandemic period was significantly higher [43][44][45]. In our study, the majority of the patients were children older than 9 years, which corresponds to the age at which appendicitis is more frequent in the pediatric population.…”

Section: Discussionmentioning

confidence: 98%

Trends and Predictors of Pediatric Negative Appendectomy Rates: A Single-Centre Retrospective Study

Jukić,

Nizeteo,

Matas

et al. 2023

Children

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Background: Appendectomy is still the standard treatment for acute appendicitis in the majority of centers. Despite all available diagnostic tools, the rates of negative appendectomies are still relatively high. This study aimed to determine negative appendectomy rates and to analyze the demographic and clinical data of the patients whose histopathology report was negative. Methods: All patients younger than 18 years who underwent appendectomy for suspected acute appendicitis in the period from 1 January 2012 to 31 December 2021 were included in the single-center retrospective study. Electronic records and archives of histopathology reports were reviewed for patients with negative appendectomy. The primary outcome of this study was a negative appendectomy rate. Secondary outcomes comprehended the rate of appendectomies and the association of age, sex, body mass index (BMI), values of laboratory markers, scoring systems, and ultrasound reports with negative histopathology reports. Results: During the study period, a total of 1646 appendectomies for suspected acute appendicitis were performed. In 244 patients, negative appendectomy was reported regarding the patients’ pathohistology. In 39 of 244 patients, other pathologies were found, of which ovarian pathology (torsion and cysts) torsion of greater omentum and Meckel’s diverticulitis were the most frequent. Finally, the ten-year negative appendectomy rate was 12.4% (205/1646). The median age was 12 years (interquartile range, IQR 9, 15). A slight female predominance was noted (52.5%). A significantly higher incidence of negative appendectomies was noted in girls, with a peak incidence between the ages of 10 and 15 years (p < 0.0001). Male children whose appendectomy was negative had significantly higher BMI values compared to female patients (p = 0.0004). The median values of white blood cell count, neutrophil count, and CRP in the patients with negative appendectomy were 10.4 × 109/L, 75.9%, and 11 mg/dL, respectively. The median of Alvarado’s score was 6 (IQR 4; 7.5), while the median of the AIR score was 5 (IQR 4, 7). The rate of children with negative appendectomy who underwent ultrasound was 34.4% (84/244), among which 47 (55.95%) concluded negative reports. The rates of negative appendectomies were not homogenous in terms of distribution regarding the season. The incidence of negative appendectomies was more frequent during the cold period of the year (55.3% vs. 44.7%; p = 0.042). Conclusions: The majority of negative appendectomies were performed in children older than 9 years and most frequently in female children aged 10 to 15 years. In addition, female children have significantly lower BMI values compared to male children with negative appendectomy. An increase in the utilization of auxiliary diagnostic methods such as computed tomography could affect the reduction in the pediatric negative appendectomy rate.

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Section: Discussionmentioning

confidence: 98%

Trends and Predictors of Pediatric Negative Appendectomy Rates: A Single-Centre Retrospective Study

Jukić,

Nizeteo,

Matas

et al. 2023

Children

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Biliary stone in patient with situs inversus totalis

Azadbakht,

Daniali

2024

International Journal of Surgery Case Reports

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The Effect of COVID-19 Lockdown on Appendicitis Severity and Management

Rodwell,

Gracias,

Seth

et al. 2024

Appendicitis - Current Insights [Working Title]

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The COVID-19 pandemic placed substantial strains on healthcare systems globally causing downstream sequalae on emergency surgical conditions including acute appendicitis. The primary aims of this study were to examine rates of complicated appendicitis, conservatively managed uncomplicated appendicitis and outcomes of acute appendicitis management before, during and after the New South Wales’ COVID-19 lockdown in Australia. Retrospective analysis of patients with acute appendicitis in a NSW local health district between 4th December 2019 and 13th October 2020 was undertaken. Patients were grouped temporally into Pre-lockdown, Lockdown or Post-lockdown groups. No significant change in the rates of complicated appendicitis during the lockdown compared to periods immediately before and after the lockdown were found. Patients with complicated appendicitis tended to be older and have longer hospital stays. Conservatively treated uncomplicated appendicitis rates did not increase during the lockdown period. The findings indicate potential for lower threshold for investigation and management of suspected acute appendicitis in older people and criteria for conservative management of uncomplicated appendicitis may require revision. Analysis of pandemic surgical rates could enhance bed management planning for future disasters, ensuring optimal patient safety. Further research is required to delineate the effect of lockdowns on acute appendicitis and may inform changes to practice.

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Comparison of the prevalence of perforated appendicitis during and before COVID19 pandemic

Cited by 3 publications

References 23 publications

Trends and Predictors of Pediatric Negative Appendectomy Rates: A Single-Centre Retrospective Study

Trends and Predictors of Pediatric Negative Appendectomy Rates: A Single-Centre Retrospective Study

Biliary stone in patient with situs inversus totalis

The Effect of COVID-19 Lockdown on Appendicitis Severity and Management

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