The purpose of this study was to determine the association between physical activity and selfreported disability in ambulatory persons with mild to moderate late effects of polio (N=81, mean age 67 years). The outcome measures were: Physical Activity and Disability Survey (PADS), a pedometer, Self-reported Impairments in Persons with Late Effects of Polio Scale (SIPP), Walking Impact Scale (Walk-12), Falls Efficacy Scale -International (FES-I) and self-reported incidence of falls. The participants were physically active on average 158 minutes per day and walked 6212 steps daily. Significant associations were found between PADS and Walk-12 (r = -0.31, p < 0.001), and between the number of steps and SIPP, Walk-12 and FES-I (r = -0.22 to -0.32, p < 0.05). Walk-12 and age explained 14% of the variance in PADS and FES-I explained 9% of the variance in number of steps per day. Thus, physical activity was only weakly to moderately associated with self-reported disability.