Comparison of Therapeutic Effects of PVP and PKP Combined With Triple Medication on Mild and Moderate Osteoporotic Vertebral Compression Fracture in the Elderly

Abstract

ObjectiveTo compare and analyze the therapeutic effect of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) combined with triple therapy on elderly patients with mild to moderate osteoporotic vertebral compression fractures (OVCF).MethodsA total of 114 cases of elderly patients with mild to moderate osteoporotic vertebral compression fractures were identified as research subjects in our hospital from January 2017 to January 2018, and a total of 136 vertebrae were included. The patients who underwent PVP operation were included as the control group with 67 injured vertebrae, and the patients who underwent PKP operation were included as the experimental group with 69 injured vertebrae.ResultsThe operation time and bone cement injection volume of the experimental group were significantly higher than the control group. The visual analog scale (VAS) scores of the two groups at 3 months and 6 months after operation were lower than those before operation, with lower VAS scores observed in the experimental group at 3 months and 6 months after operation. The anterior height of the vertebral body in the experimental group was higher than that of the control group. The experimental group outperformed the control group in the incidence of postoperative complications. The postoperative Oswestry dysfunction index (ODI) scores of the two groups were lower before the operation, in which the experimental group had lower scores than the control group (P < 0.05).ConclusionPVP and PKP combined with postoperative triple therapy can achieve a promising analgesic effect. PKP has a higher volume of bone cement injection volume, and a lower incidence of complications, which gives rise to a better vertebral body recovery height than that of PVP, with rapid postoperative body function recovery and good quality of life.

Treatment for Osteoporotic Vertebral Fracture - A Short Review of Orthosis and Percutaneous Vertebroplasty and Balloon Kyphoplasty

“…Further high-quality multicenter randomized controlled tri-als with longer follow-up and larger sample sizes are needed, but at this time indicate that there are no significant differences between PVP and BKP in terms of VAS score, ODI score, or cement leakage, and that both are useful treatments for patients with OVF. [25][26][27][28][29][30][31][32][33][34] On the other hand, a systematic review comparing BKP and PVP, focusing on the primary outcome of height restoration and the secondary outcomes of pain relief and function (33 total randomized controlled trials; 20 BKP, 7 PVP, and 6 comparing PVP to BKP), suggested that BKP may be superior in restoring vertebral height, but both procedures restored some vertebral height reduction, kyphosis, Cobb angle, and wedge angle, and showed benefit in pain reduction and patient-reported functional improvement. However, it is not possible to definitively conclude whether BKP or PVP is superior in reducing pain and restoring function because many studies that examined all 3 variables did not report statistically significant results, and more definitive studies and data analysis are needed to confirm this finding (Figs.…”

Unilateral Percutaneous Kyphoplasty Using a Novel Guide Device for Thoracolumbar Osteoporotic Vertebral Fracture

“…[5][6][7][8] Percutaneous kyphoplasty (PKP) is a rapid, effective, and minimally invasive technique for treating TLOVFs in elderly patients, and it can speed recovery of function and improve quality of life with fewer complications compared with conservative treatment. [9][10][11][12][13] However, surgeons are heavily dependent on image-guided navigation, especially when the surgeon is inexperienced. The radiation dose of the operator was highest in C-arm-guided minimally invasive spine surgery.…”