Comparison of thermodilution, lithium dilution, and pulse contour analysis for the measurement of cardiac output in 3 different hemodynamic states in dogs

Abstract

Both LiDCO and PiCCOTD agreed well with PAC-TD for the measurement of CO under different hemodynamic conditions. Moreover, PiCCOc appears to be an accurate method for monitoring continuous CO in dogs as its performance for measurement was similar to that of PulseCO.

Evaluation of agreement and trending ability between transpulmonary thermodilution and calibrated pulse contour and pulse power cardiac output monitoring methods against pulmonary artery thermodilution in anesthetized dogs

“…The PiCCO data used for comparison against LiDCO in that report were recorded directly after calibration with TPTD, and therefore the accuracy of continuous PiCCO was not evaluated. In the most recent report by Morgaz et al, neither accuracy nor precision data for the continuous PiCCO and PulseCO compared to PATD in dogs were presented, so comparisons to our study are not possible. The current study followed PiCCO measurements during 240 minutes without recalibration and resulted in a low concordance rate of 77% with wide RLOA.…”

“…The mean bias of −0.66 L/min between PATD and TPTD found in the current study, is larger than in previous reports in dogs that measured a mean bias of −0.04 L/min 8 or −0.04 L/min/m 2 . Overestimation of CO by TPTD compared to PATD is thought to occur due to loss of thermal indicator over the vasculature .…”

“…In 1, adequate accuracy and precision were found during exsanguination and resuscitation in 17 dogs . In a more recent study, TPTD resulted in a high accuracy with low precision in 14 dogs exposed to 3 different hemodynamic states …”

Clinical monitoring of cardiac output assessed by transoesophageal echocardiography in anaesthetised dogs: a comparison with the thermodilution technique

“…The decrease in arterial pressure was expected since isoflurane is an anaesthetic drug that reduces vascular resistance and that can be used as an inductor of hypotension in dogs undergoing experimental studies [18]. Despite an increase in HR expected during hypotension, this was not observed due to a decrease in the baroreflex induced by isoflurane and due to an increase in parasympathetic activity caused by fentanyl [19].…”

“…Both techniques were applied after 20 min of anaesthetic stabilisation at a MAP of 65–80 mmHg (normotension) and then at an MAP <65 mmHg (hypotension) induced by increasing the ET ISO [18]. Arterial hypotension was treated immediately after measuring CO by reducing ET ISO to baseline values.…”