Comparison of three oxidative stress biomarkers in a sample of healthy adults

Watters, Joanne L.; Satia, Jessie A.; Costa, Kerry-Ann da; Boysen, Gunnar; Collins, Leonard B.; Morrow, Jason D.; Milne, Ginger L.; Swenberg, James A.

doi:10.1080/13547500903183954

Cited by 2 publications

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“…This percentage roughly corresponds to the difference in this oxidative stress marker between those who are of normal weight and those who are obese. 44 Furthermore, based on the total cohort, we have 80% power to find an HR of 1.35 for all-cause mortality.…”

Section: Statistical Methods and Power Analysesmentioning

confidence: 99%

The developmental origins of ageing: study protocol for the Dutch famine birth cohort study on ageing

Rooij

Roseboom

2013

BMJ Open

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IntroductionEvidence from animal studies suggest that the rate of ageing may be influenced not only by genetic and lifestyle factors, but also by the prenatal environment. We have previously shown that people who were exposed to famine during early gestation performed worse on a selective attention task, which may be a first sign of cognitive decline, and were on average 3 years younger at the time of coronary artery disease diagnosis. Women in this group seem to die at a younger age. We hypothesise that an accelerated ageing process, set in motion by the poor prenatal environment, underlies these findings.Methods and analysisThe Dutch Famine Birth Cohort consists of 2414 men and women born in Amsterdam as term singletons around the time of the Dutch famine. In a subsample of 150 cohort members, who now are about 68 years of age, we are currently measuring cognitive decline and the incidence of white matter hyperintensities and cerebral microbleeds (through MRI), incidence of fractures, grip strength and physical performance, visual acuity and incidence of cataract operations. In this same subgroup, we will assess telomere length, oxidative stress and inflammatory status as potential underlying mechanisms. Furthermore, in the entire cohort, we will assess mortality as well as hospital admissions for age-related diseases up to the age of 68 years.Ethics and disseminationThe study was approved by the local medical ethics committee (Academic Medical Centre, University of Amsterdam) and is being carried out in agreement with the Declaration of Helsinki. All participants give written informed consent. Study findings will be widely disseminated to the scientific public as well as to the medical society and general public.

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Section: Statistical Methods and Power Analysesmentioning

confidence: 99%

The developmental origins of ageing: study protocol for the Dutch famine birth cohort study on ageing

Rooij

Roseboom

2013

BMJ Open

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“…However, it should be kept in mind that the results produced by measuring, for example, 10 unreliable biomarkers are equally untrust worthy to those produced by a single unreliable biomarker. Indeed, even within the same biomarker category (for instance, DNA oxidation or lipid peroxidation), the corresponding biomarkers, which presumably indicate the same type of oxidative modifications, may provide partially or completely dif ferent responses to the same oxidant stimulus (Breusing et al 2010;Watters et al 2009). This is not surprising, since each biomarker is a product of a specific chemi cal reaction.…”

Section: Question 2: How Many Redox Biomarkers To Measure?mentioning

confidence: 99%

Antioxidants in Sport Nutrition

Lamprecht¹

2014

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This book contains information obtained from authentic and highly regarded sources. Reasonable efforts have been made to publish reliable data and information, but the author and publisher cannot assume responsibility for the validity of all materials or the consequences of their use. The authors and publishers have attempted to trace the copyright holders of all material reproduced in this publication and apologize to copyright holders if permission to publish in this form has not been obtained. If any copyright material has not been acknowledged please write and let us know so we may rectify in any future reprint.The Open Access version of this book, available at www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation without intent to infringe. Library of Congress Cataloging-in-Publication DataAntioxidants in sport nutrition / edited by Manfred Lamprecht. pages cm Summary: "Antioxidant use in sports is controversial due to existing evidence that it both supports and hurts athletic performance. This book presents information on antioxidants, specifically for athletes, and their roles in sports nutrition. It stresses how antioxidants affect exercise performance, health, and immunity. Chapters cover oxidative stress; basic nutrition for athletes; major dietary antioxidants; sports supplements; performance/adaptation to exercise; antioxidants role in health and immunity; reviews on vitamins C, E, beta carotene, and minerals in sports nutrition; and roles polyphenols play in high-performance sport"--Provided by publisher.Includes bibliographical references and index.

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Comparison of three oxidative stress biomarkers in a sample of healthy adults

Cited by 2 publications

References 0 publications

The developmental origins of ageing: study protocol for the Dutch famine birth cohort study on ageing

The developmental origins of ageing: study protocol for the Dutch famine birth cohort study on ageing

Antioxidants in Sport Nutrition

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