2023
DOI: 10.1186/s12903-023-03385-1
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Comparison of topical purslane & topical 0.1% triamcinolone acetonide in the management of oral lichen planus - a double blinded clinical trial

Arul Jothi Murugan,
Anuradha Ganesan,
Yesoda K. Aniyan
et al.

Abstract: Aim and background Oral lichen planus (OLP) is a chronic autoimmune mucocutaneous disorder of unknown etiology and treatment is targeted at alleviating symptoms. At present, corticosteroids are the mainstay treatment, and their side effects hamper their long-term use, demanding alternative therapy. This study intended to assess the efficacy of topical purslane (Portulaca oleracea) at two concentrations, 5% and 10%, in OLP and to compare the level of clinical improvement in comparison to topical… Show more

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Cited by 2 publications
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“…Numerous alternative treatment protocols have also been studied in recent years and natural biologically active compounds with potential health benefits like phytochemicals have shown promising results with reduced side effects and similar anticancer effects. Various mechanisms have been explored by phytochemicals in regulating epigenomics, targeting cancer stem cells, improving human immunity, promoting cancer cell apoptosis, cell cycle arrest, down regulation of cell cycle regulators, as well as enhancing tumor suppression (4,5).…”
Section: Introductionmentioning
confidence: 99%
“…Numerous alternative treatment protocols have also been studied in recent years and natural biologically active compounds with potential health benefits like phytochemicals have shown promising results with reduced side effects and similar anticancer effects. Various mechanisms have been explored by phytochemicals in regulating epigenomics, targeting cancer stem cells, improving human immunity, promoting cancer cell apoptosis, cell cycle arrest, down regulation of cell cycle regulators, as well as enhancing tumor suppression (4,5).…”
Section: Introductionmentioning
confidence: 99%