Comparison of two measurements for the lower lid margin thickness: vernier micrometer and anterior segment optical coherence tomography

Wang, Dahu; Yao, Jie; Liu, Xinquan

doi:10.1007/s10792-020-01505-2

Cited by 4 publications

(26 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although the LMT is difficult to measure, people are still trying to measure it with several different methods [15][16][17][28][29][30]. Hykin et al [8] suggested that the lid margin width in normal adults including wet mucosa was approximately 2.5 mm.…”

Section: Discussionmentioning

confidence: 99%

“…This was a single-center, prospective, cross-sectional, observational study, which was an extension of our previous works [15][16][17]. In this study, 100 volunteers (40 males and 60 females) aged 20 to 79 years were recruited from the ophthalmic clinic of Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, including 56 participants with healthy eyes and 44 participants with MGD.…”

Section: Participantsmentioning

confidence: 99%

“…Study Exclusion Criteria [15][16][17]: irregular lid margin structures-cicatrices, dimpling or notching, serration; meibomian gland loss area [ 33% of the total area in each eyelid [4]; history of chalazion or hordeolum within the past 3 months; eyelid tattoos; ocular surface disease index (OSDI) score\12 points in MGD subjects; active ocular allergies; ocular infection/inflammation; entropion and trichiasis; eyelid tumor; no eyelashes or central eyelashes loss; conjunctivochalasis; nystagmus; paralytic strabismus; have worn contact lens within the past 3 months; had a history of intraocular surgery or ocular surgery; used isotretinoin (accutane) within the past 6 months; autoimmune disease requiring systemic treatment; was pregnant or lactating.…”

Section: Participantsmentioning

confidence: 99%

“…Through the previous studies [15][16][17], we found that the LMT from the posterior lash line to the mucocutaneous junction (MCJ) was a relatively constant feature of the lid margin in normal adults and could be quantitatively measured by anterior segment optical coherence tomography (AS-OCT), oculus keratograph and vernier micrometer (VM). However, we only reported the data of the lower LMT, not the data of the upper LMT.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Measurement of the Lid Margin Thickness in Meibomian Gland Dysfunction with Vernier Micrometer

et al. 2021

Self Cite

View full text Add to dashboard Cite

Introduction To investigate the lid margin thickness (LMT) from the posterior lash line to the mucocutaneous junction at the middle position in adults with and without meibomian gland dysfunction (MGD) by vernier micrometer (VM). Methods This is a cross-sectional, observational study. A hundred eyes from 100 volunteers aged 20 to 79, including 56 normal participants and 44 participants with MGD, were recruited. Measurements of the LMT by VM were performed by the same person. Results The mean age of 56 normal subjects (24 males and 32 females) and 44 MGD subjects (16 males and 28 females) was 40.0 ± 13.2 years and 42.7 ± 17.1 years, respectively. There was a significant difference in the upper LMT between normal and MGD subjects (1.36 ± 0.25 vs. 1.60 ± 0.27 mm, P < 0.001), but not in the lower LMT (1.0 ± 0.23 vs. 1.10 ± 0.28 mm, P = 0.07). In both normal and MGD subjects, the upper or lower LMT was significantly positively correlated with age ( P < 0.05), and the upper LMT was greater than the lower LMT ( P < 0.001). In addition, the lower LMT in MGD subjects was significantly positively correlated with meibum expressibility ( r s = 0.35, P = 0.02). Conclusions The LMT was closely related to age and could be an important indicator for detecting MGD. Furthermore, we found that the upper LMT was greater than the lower LMT, and the lower LMT in MGD subjects seemed to be related to meibum expressibility.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Participantsmentioning

confidence: 99%

Section: Participantsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Measurement of the Lid Margin Thickness in Meibomian Gland Dysfunction with Vernier Micrometer

et al. 2021

Self Cite

View full text Add to dashboard Cite

show abstract

“…By comparing AS-OCT scans with IR light scans, the researchers revealed a 3-scale classification system based on MG acini and ducts (Group 1 = constricted acini, Group 2 = atrophic acini, Group 3 = no acini), which might help clinicians to further assess and treat MG patients. Wang et al (2020) proposed a new application of AS-OCT for patients in the early stages of MGD or completely asymptomatic: in their research, they measured the lower lid margin thickness (LLMT) from the posterior lash line to the Marx's line and compared the results with a vernier micrometre (e.g., ruler). The reason behind this methodology is that thickening of the lid margin is a common feature of MGD (Knop et al, 2011), but also of blepharitis, lid wiper epitheliopathy, etc.…”

Section: Anterior Segment Optical Coherence Tomographymentioning

confidence: 99%

Imaging the tarsal plate: A Mini-Review

Recchioni

2021

Scand J Optom Vis Sci

View full text Add to dashboard Cite

Imaging the tarsal plate and the meibomian glands (MG) grants new opportunities for ophthalmic practitioners who work in the field of the ocular surface and dry eye across the globe. The secretory role of MG plays a fundamental part in protecting the moisture in front of the eye surface by creating an active shield made of meibum (lipid) which prevents tear evaporation and causes dry eye. Evidence from the most popular Dry Eye Workshop reports (2007 and 2016) demonstrate that MG dysfunction is the first cause of evaporative dry eye which is also the most common cause of dry eye and ocular surface discomfort. Fortunately, during the last years, a plethora of new devices for MG observation, diagnosis and follow-up have been made available in the market. These devices range from invasive to minimally invasive, high to low-tech and from being expensive to low-cost. The objective of this mini-review is to condense the latest evidence in MG imaging by providing a narrative overview on the most common technologies plus some other newer aspects which might guide clinicians and researchers in the field of the ocular surface and dry eye.

show abstract

Application of optical coherence tomography and keratograph in the measurements of lower lid margin thickness

Wang

Tang

Xiao-jun

et al. 2023

Graefes Arch Clin Exp Ophthalmol

Self Cite

View full text Add to dashboard Cite

Purpose This study aims to investigate the applicability of lower lid margin thickness (LLMT) measurements in adults with and without meibomian gland dysfunction (MGD) by optical coherence tomography (OCT) and keratograph. Methods This is a cross-sectional, observational study. A hundred and eight volunteers aged 20 to 79, including 68 MGD patients and 40 normal subjects, were recruited. Using OCT and keratograph to measure the LLMT from the posterior lash line to anterior edge or outer edge of the tear meniscus was separately performed two times by the same person. Results The mean age of normal and MGD subjects was 50.5 ± 14.2 years and 55.8 ± 15.5 years, respectively. The LLMT with OCT and keratograph in MGD patients was significantly greater than that in normal subjects (1.06 ± 0.27 and 1.03 ± 0.25 mm vs. 0.90 ± 0.20 and 0.86 ± 0.16 mm, respectively). In both normal and MGD subjects, the tear meniscus height and LLMT with OCT were both greater than that with keratograph (P < 0.05), and intraclass correlation coefficient (ICC) demonstrated a good agreement in the LLMT measurements between two devices (ICC = 0.83 and 0.79, respectively). Additionally, the LLMT in MGD patients was appeared to be positively correlated with meiboscore (rs = 0.37, P = 0.002). Conclusions The OCT and keratograph were two reliable tools in the LLMT measurements, which may have potential applications for diagnosis and evaluation of MGD. Furthermore, we found that the LLMT measured by OCT was greater than that measured by keratograph.

show abstract

Comparison of two measurements for the lower lid margin thickness: vernier micrometer and anterior segment optical coherence tomography

Cited by 4 publications

References 40 publications

Measurement of the Lid Margin Thickness in Meibomian Gland Dysfunction with Vernier Micrometer

Measurement of the Lid Margin Thickness in Meibomian Gland Dysfunction with Vernier Micrometer

Imaging the tarsal plate: A Mini-Review

Application of optical coherence tomography and keratograph in the measurements of lower lid margin thickness

Contact Info

Product

Resources

About