Comparison of two vasoconstrictors on glycemic levels in diabetic patients

What’s new for the clinician? - Excerpts from and summaries of recently published papers

“…Type 1 DM (DM1) is an autoimmune disease destroying pancreatic β cells, leading to poor insulin production. 1 Type 2 DM (DM2) has multifactorial causes, it is usually associated with obesity, hypertension, and dyslipidemia, and affects both β cell function and insulin tissue sensitivity.…”

“…Some authors have reported an increase in blood glucose levels after the administration of local anesthetics containing adrenaline as vasoconstrictor. 1 The recommended anesthetics in these patients may be 3% mepivacaine without vasoconstrictor or 3% prilocaine with 0.03 IU/mL felypressin. 1 Felypressin is indicated in non-controlled diabetic patients because it does not activate �-nor β-adrenergic receptors.…”

“…1 The recommended anesthetics in these patients may be 3% mepivacaine without vasoconstrictor or 3% prilocaine with 0.03 IU/mL felypressin. 1 Felypressin is indicated in non-controlled diabetic patients because it does not activate �-nor β-adrenergic receptors. 1 However, it presents some disadvantages, such as deficient hemostasis control and short pulpal anaesthesia.…”

“…Among local anaesthesia methods, the inferior alveolar nerve block (IANB) is frequently used to ensure pain control prior to procedures such as restoration of mandibular primary and permanent molar teeth, endodontic treatments, and surgical interventions. 1 This was a randomized, controlled cross-over clinical trial with 60 children, aged 6-12 years. Healthy, cooperative (exhibiting "positive" and "absolutely positive" behaviour on the Frankl Behaviour Scale (FBS)) children requiring IANB for dental treatments (restorative and endodontic procedures) on their bilateral mandibular primary or permanent molars were included in the study.…”

“…Various methods have been investigated for preventing the pain of an IANB, such as applying topical anesthetics prior to the injection, warming or buffering the solution prior to administration, using a computer-controlled anaesthesia delivery system such as the Wand system, and employing modern devices, like DentalVibe that uses vibration and the two-stage injection technique. 1 Comfort-in™ (Korea), one of the more recent dental devices, was developed to administer local anaesthesia using a needle-free injection method. The developers of this system claim that it is an easy to use, virtually pain-free, needle-free jet injector system, which eliminates the fear, pain, and danger of needles from the injection process.…”