Periarthritis shoulder also called as Adhesive capsulitis or Frozen shoulder. The body creates excessive adhesion across the glenohumeral joint as a result of the idiopathic, chronic, and indolent degenerative process known as periarthritis shoulder, which causes discomfort, stiffness, and a reduction in range of motion. In the general population, the prevalence of adhesive capsulitis is 3-55%, and it is 20% in those with diabetes. Many types of treatment have been employed in the treatment of shoulder disorder such as simple analgesia, NSAIDS, intraarticular steroid, platelet rich plasma injection and surgery. PRP is more efficient and long-lasting than cortisone injection for the treatment of adhesive capsulitis, according to several research.To evaluate the outcome of Periarthritis shoulder treated with Platelet Rich Plasma by comparing the intensity of pain, degree of increase in angle of movements of shoulder.It is a randomized control trial with total of 30 patients between age group of 30–70 years old of both sex being diagnosed for the first time and not treated by any other modality are taken up for the study.Patients having chronic pain due to other causes like nerve damage or other neurological disorders, history of fracture around the shoulder joint, patients having local skin infection at the shoulder joint and patient not giving informed consent form to be a part of study were excluded from the study. Under sterile aseptic condition Autologous Platelet Rich Plasma of 4 ml was injected into the shoulder joint. It was a randomized single blinded controlled trial with 1 month, 3 months & 6 months follow up in which outcome was measures using visual analogue scale, ROM, SPADI.Using the paired t test, descriptive and inferential statistical analysis were performed inthe current study. The mean VAS score at 6 months was reduced from 6.66+2.499 to 3.4±1.473; Mean SPADI Score at 6 month increased from 50.53±14.811 to 76.76±10.926; At 6 month Flexion increased from 66 to 116.33, extension increased from 18.6 to 31.33 and abduction increased from 87.33 to 126.833 with p value of 0.0001 which is statistically significant.This study concluded that platelet rich plasma injection causes decrease in intensity of pain and increase in angle of movements of shoulder in patients of periarthritis shoulder.